Recommendations on Acute Kidney Injury Biomarkers From the ...

Biomarkers of Acute Kidney Injury - Annual Reviews

Acute kidney injury (AKI) is a common condition with a high risk of death. The standard metrics used to define and monitor the progression ...

Biomarkers in acute kidney injury: On the cusp of a new era? - JCI

The search for a better biomarker of acute kidney injury (AKI) to replace serum creatinine has been long and elusive (1). The field of ...

Recommendations on Acute Kidney Injury Biomarkers From the ...

IMPORTANCE In the last decade, new biomarkers for acute kidney injury (AKI) have been identified and studied in clinical trials. Guidance is ...

Biomarkers of acute kidney injury: the pathway from discovery to ...

In pediatric patients, urinary L-FABP was found to be a sensitive early biomarker of AKI after CPB surgery [54], [113]. Higher urinary L-FABP ...

Acute Kidney Injury Biomarkers, AKI Assays - bioMerieux

It affects more than 70% of intensive care units (ICU) patients1,2. In critical care settings, current diagnosis tools are lagging, so prevention is key. An ...

Machine Learning in Diagnosing Acute Kidney Injury

Using a continuous random forest analysis technique, the authors first trained and subsequently validated its utility in identifying patients with acute kidney ...

Biomarker-Guided Risk Assessment for Acute Kidney Injury

The most recent Kidney Disease Improving Global Outcomes practice guidelines for AKI have restated the importance of earliest possible ...

a comprehensive review of biomarkers in acute kidney injury

This comprehensive review explored the evolving landscape of biomarkers of acute kidney injury (AKI), emphasizing their critical role in early detection, ...

The Role of Cell Cycle Arrest Biomarkers for Predicting...

According to the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines, AKI is diagnosed based on changes in kidney function such as rise in serum ...

Investigational biomarkers and the evaluation of acute kidney injury

Urinary tubular enzymes · Urinary low-molecular-weight proteins · Neutrophil gelatinase-associated lipocalin (NGAL) · Urinary kidney injury ...

Biomarkers Consortium – Clinical Evaluation and Qualification of ...

When conducting clinical trials of any drugs that could cause acute kidney injury, Researchers need biomarkers that can detect such injuries both to ensure ...

Acute kidney injury biomarkers and hydration assessments following ...

Urinary [IGFBP7·TIMP-2] and other AKI biomarkers were measured following the 24-h protocols. Diagnostic accuracy was assessed via receiver operating ...

AKI Biomarkers / Therapeutic Targets - Waikar Lab

We are interested to identify biomarkers that may suggest therapeutic targets. For example, we have studied dysregulated mineral metabolism and iron toxicity.

Acute Kidney Injury and AKI Biomarkers in the ICU - John Kellum, MD

Comments8 · Biomarkers of Acute Kidney Injury - K. · KDIGO-ISN Webinar on AKI in 2019: What has changed since the KDIGO guidelines in 2012? · MAP ...

Acute Kidney Injury (AKI) Treatment & Management

Kidney Disease: Improving Global Outomes (KDIGO) guidelines recommend against using low-dose dopamine for prevention or treatment of AKI, and ...

Review of the limitations of current biomarkers in acute kidney injury ...

Hence, the current guidelines are still developing to improve and understand the clinical implications of risk factors and earlier predictive ...

New kidney biomarkers: A faster way to detect acute kidney injury

NGAL, KIM-1, TIMP-2, and ILGFBP7 levels give early warning of kidney injury. Unfortunately, few clinicians are aware of these new options for ...

Laboratory Investigation of Acute Kidney Injury - ADLM

Cystatin C has been proposed as a biomarker for earlier detection of changes in kidney function. However, most forms of AKI primarily involve ...

New biomarkers in acute kidney injury - Taylor & Francis Online

This, in turn, delays any putative measures to treat AKI or to limit its degree. Consequently, efforts have focused on new biomarkers associated with AKI that ...

Definition and biomarkers of acute renal damage: New perspectives

The serum and urine biomarkers (creatinine, urea, and diuresis) currently in use are not sensitive or specific for detecting kidney damage, limiting treatment ...