Role of ketamine in refractory neonatal seizures

Refractory and super-refractory status epilepticus and evidence for ...

In more than 70% of studies regarding seizures controlled with ketamine during the first 48 hours of treatment, it is evi- dent that this drug ...

Intravenous Ketamine Bolus(es) for the Treatment of Status ...

Prolonged seizure activity is also associated with overexpression of N-methyl-D-aspartic (NMDA) receptors. Rodent models have shown the efficacy ...

Novel Therapeutics for Neonatal Seizures - Neurotherapeutics

... role of lidocaine in the treatment of neonatal seizures. Until such data ... Use of ketamine in a newborn with refractory status epilepticus: A case report.

outcome of therapies in refractory and super-refractory convulsive ...

However, seizures recurred on withdrawal in 41% and two patients (7%) switched due to side-effects. As with ketamine, the inhalational anaesthetics were usually ...

The Role of Glutamate Receptors in Epilepsy - MDPI

In such situations, ketamine, a noncompetitive NMDA antagonist, is an option for late, refractory SE. Ketamine has been shown to play a role in the treatment of ...

Transition from intravenous to enteral ketamine for treatment of ...

Nonconvulsive status epilepticus (NCSE) is a diagnosis that is often challenging and one that may progress to refractory NCSE. Ketamine is a ...

Ketamine Infusion for Super Refractory Status Epilepticus in ...

Status epilepticus. (SE) is reported in patients with AHC with the common occurrence of refractory SE due to failure of cessation of seizures ...

Ketamine Efficacy for Management of Status Epilepticus - Handtevy

13 At this point, a prehospital clinician will likely be directed to contact online medical direc- tion if seizures persist for benzodiazepine- refractory SE.

KoreaMed Synapse

The response to treatment, its evolution time and duration, and the need to use one or more antiseizure drugs define SE as refractory or super- ...

A Comparison of Ketamine and Midazolam as First-Line Anesthetic ...

Among children and neonates with RSE, ketamine was more often followed by seizure termination and less often associated with adverse effects ...

Review Article Early Use of the NMDA Receptor Antagonist ...

Prospective study of early implementation of ketamine should shed light on the role of such medications in RSE. 1. Introduction. Refractory status epilepticus ( ...

Ketamine Implicated in New Onset Seizure

Recent studies have shown the benefit of ketamine for refractory status epilepticus; however, this application of the drug is still being ...

How close is ketamine to routine use in refractory status epilepticus?

pediatric conditions (e.g. newborn intracranial hemorrhage, pul- ... Overexcitation of glutamatergic neurons also plays an important role in ...

Continuous infusion, general anesthesia and other

Pentobarbital infusion for refractory status epilepticus (RSE). Ketamine. Prolonged seizures are accompanied by a decline in sensitivity to GABA agonists ...

Ketamine: An Update for Obstetric Anesthesia

Instead, ketamine successfully treated seizures induced by NMDA [66] or electrical stimulation [67], and stopped refractory status epilepticus [68,69]. Although ...

The treatment of super-refractory status epilepticus: a critical review ...

If seizures continue despite this therapy, the patient is said to be in Stage 2 (established status epilepticus) and therapy is with intravenous ...

Ketamine for Refractory Status Epilepticus? - Medscape

Ketamine, used for analgesia and sedation, is increasingly being used to treat refractory status epilepticus, but only for the most ...

Refractory and Super-refractory Status Epilepticus - Indian Pediatrics

We have summarized these in Table I, and briefly discuss the role of electroencephalography (EEG) ... Increasing ketamine use for refractory status epilepticus in ...

Novel drugs and early polypharmacotherapy in status epilepticus

Non-anesthetic effects of ketamine, a review article. M ... Use of ketamine in a newborn with refractory · status epilepticus: a case report.

Seizure - Renaissance School of Medicine

The role of mitochondria in status epilepticus. Epilepsia 2007;48 ... Increasing · ketamine use for refractory status epilepticus in US pediatric hospitals.