Rotors have been demonstrated to drive human atrial fibrillation

Ionic and substrate mechanisms of atrial fibrillation: rotors ... - Elsevier

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in humans, however its mechanisms are poorly understood and its therapy is often ...

Mapping of Atrial Fibrillation - Erasmus University Rotterdam

CrossTalk proposal: Rotors have been demonstrated to drive human atrial ... Cardiac fibrillation: from ion channels to rotors in the human heart. Heart ...

Modeling Atrial Fibrillation using Human Embryonic Stem Cell ...

We induced stable re-entrant spiral wave geometries (called rotors), which act as arrhythmogenic self-organized drivers in AF, using rapid ...

Temporal stability of the atrial fibrillation cycle length in persistent ...

importance of rotors in human AF remains unclear. ... Background: A degree of spatiotemporal organisation has been demonstrated in human AF, but stability of the ...

The role of rotors in atrial fibrillation - AME Publishing Company

... rotors and focal sources in either atrium. Ablation of such sources (Focal Impulse and Rotor Modulation: FIRM ablation) has been shown to improve ablation.

Dynamical anchoring of distant arrhythmia sources by fibrotic ...

Ablation targeting rotor sites has resulted in arrhythmia termination. Recent clinical, experimental and modelling studies demonstrate that rotors are often ...

Phase synchrony reveals organization in human atrial fibrillation

Although the spatial resolution of techniques such as focal impulse and rotor mapping (FIRM) have been shown to be able to map human spiral waves (26), spatial ...

Long-term Follow-up of FIRM-guided Ablation of Atrial Fibrillation

ABSTRACT. Radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF) guided by focal impulse and rotor modulation (FIRM) has been shown ...

RESEARCH - Stanford University

Ablation of human AF rotors has been shown to terminate AF in many patients, and to improve the success of ablation. Many of these results have been ...

Presence and stability of rotors in atrial fibrillation

Initial efforts in locating rotors in human AF have used sequential or ... Crosstalk proposal: rotors have been demonstrated to drive hu- man atrial fibrillation.

Ablation of long-standing persistent atrial fibrillation - Mody

However, the importance of rotors to human AF remains controversial. More recently, high resolution mapping has shown some evidence that dissociated ...

The continuous challenge of AF ablation: From foci to rotational activity

Ablation of rotational or focal sources for AF, which lie outside the pulmonary veins in many patients, is a practical approach that has been shown to improve ...

Entropy Mapping Approach for Functional Reentry Detection in Atrial ...

Catheter ablation of critical electrical propagation sites is a promising tool for reducing the recurrence of atrial fibrillation (AF).

Ablating Atrial Fibrillation: Customizing Lesion Sets Guided by Rotor ...

This debate has been invigorated by the advent of novel clinical mapping, which has recently revealed stable rotors and focal sources25 that appear to sustain ...

Atrial fibrillation - European Journal of Internal Medicine

The role of RAS in atrial remodeling to sustain AF in humans is less clear. Angiotensin II infusion in human subjects has not been shown to ...

HHS Public Access - eScholarship

CrossTalk proposal: rotors have been demonstrated to drive human atrial ... Long-term outcomes after catheter ablation for atrial fibrillation (AF) have been.

Ionic Determinants of Functional Reentry in a 2-D Model of Human ...

Recent studies suggest that atrial fibrillation (AF) is maintained by fibrillatory conduction emanating from a small number of high-frequency reentrant ...

Simple Model for Identifying Critical Regions in Atrial Fibrillation

Atrial fibrillation (AF) is a poorly understood arrhythmia where multiple activation wave fronts are observed to propagate continuously in the ...

(PDF) Rotor mapping and ablation to treat atrial fibrillation | Junaid ...

... drive atrial fibrillation ... has been hypothesized and now demonstrated to cause human fibrillation (Fig. ... human atrial fibrillation have been addressed by ...

Real-Time Rotational Activity Detection in Atrial Fibrillation - Frontiers

Rotational activations, or spiral waves, are one of the proposed mechanisms for atrial fibrillation (AF) maintenance. We present a system for assessing the ...