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Soft Substrates Containing Hyaluronan Mimic the Effects ...


NIH Public Access - Kumar Lab

However, the biophysical basis of HA molecular weight effects ... Interactive Substrates Using Hyaluronic Acid Hydrogels with Tunable Mechanical Properties.

Substrate viscosity impairs temozolomide-mediated inhibition of ...

Janmey,. Soft substrates containing hyaluronan mimic the effects of increased stiffness on morphology, motility, and proliferation of glioma ...

Hydrogel scaffolds as in vitro models to study fibroblast activation in ...

... HA having no effect on fibroblast behavior to reports of HA increasing myofibroblast activity. ... substrates and then soft substrates was ...

Hypoxia impacts human MSC response to substrate stiffness during ...

0.167 (soft) or 49.6 kPa (stiff) in chondrogenic medium containing ... Indeed, our findings suggest that soft TE scaffolds that mimic the soft ...

In Vivo Stimulation of De Novo Collagen Production Caused by ...

Results Compared with controls, immunostaining in skin receiving cross-linked hyaluronic acid injections revealed increased collagen deposition around the ...

Hyaluronic Acid and Its Derivatives in Coating and Delivery Systems ...

(4) viscoprotection – As it was discussed previously, due to interactions with different cell receptors and other proteins, and its antioxidant ...

Hyaluronan (HA) Interacting Proteins RHAMM and Hyaluronidase ...

To study the individual functions of hyaluronan interacting proteins in prostate cancer (PCa) motility through connective tissues, we developed a novel ...

The Role of Hyaluronic Acid and Its Receptors in the Growth and ...

Signaling effects of hyal- uronic acid receptors will be discussed, with a focus on CD44. The implications of CD44 enrich ment in cancer stem cells will be ...

Cell response to extracellular matrix viscous energy dissipation ...

The mechanics of the extracellular matrix (ECM) determine cell activity and fate through mechanoresponsive proteins including Yes-associated ...

Actuating Extracellular Matrices Decouple the Mechanical and ...

... substrates with microscale topography that enable stable cell–substrate tethering. ... substrate-dependent effects. We followed established ...

The Role of Myosin-II in Cell Spreading on Soft Hyaluronan ...

In contrast, cells in contact with one another show no significant effect. The spreading, shape and cytoskeletal morphology of single cells on ...

Hyaluronic acid mimics and methods related thereto - Google Patents

Also provided are HA mimics comprising a polypeptide comprising double hydrophobic residues, wherein said mimic binds to the hyaluronic acid binding domain of ...

Hyaluronic acid - Wikipedia

Hyaluronic acid also called hyaluronan, is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, ...

Hyaluronans in the Shoulder - ShoulderDoc

Hyaluronan (HA) is a naturally occurring polymer found in high concentrations in joints. It has a number of functions in the joint of which the main being it ...