The Regulation of Exosome Generation and Function in ...

Hsp20-Mediated Activation of Exosome Biogenesis in ...

Together, our study for the first time shows that Hsp20 could activate exosome generation/secretion in cardiomyocytes, and such exosomes could ...

Next Generation Nanotherapeutics with Extracellular Vesicles | IJN

Exosomes are a subset of EVs and are small membrane vesicles of endocytic origin that function as signalosomes and transmit amounts of bioactive ...

Extracellular Vesicles: Exosomes and Microvesicles, Integrators of ...

An important question is why some MVBs fuse with the lysosomal compartment, whereas others fuse with the plasma membrane resulting in exosome ...

Review Article - KoreaMed Synapse

Exosomes participate in intercellular communication by delivering their contents to recipient cells, with or without direct contact between ...

High frequency acoustic cell stimulation promotes exosome ...

High frequency acoustic cell stimulation promotes exosome generation regulated by a calcium-dependent mechanism.. Communications Biology, 3 ...

The Machinery of Exosomes: Biogenesis, Release, and Uptake - MDPI

Exosomes are a subtype of membrane-contained vesicles 40–200 nm in diameter that are secreted by cells into their surroundings.

Exosome-based Delivery Vehicle Feature Summary - Creative Biolabs

The recipient cell internalizes the exosome carrier and acquires its released cargos of proteins, nucleic acids, and lipids, thus enabling the regulation of ...

Exosome-Mediated Impact on Systemic Metabolism - Annual Reviews

Exosomes are small extracellular vesicles that carry lipids, proteins, and microRNAs (miRNAs). They are released by all cell types and can ...

Extracellular vesicles: The next generation in gene therapy delivery

26 Due to their profound regulatory potential and natural occurrence in EVs,. miRNA and AGO2-binding shRNAs appear to be great candidates for EV therapeutics.

A guide to the expanding field of extracellular vesicles and their ...

37 Kilchert C, Wittmann S & Vasiljeva L (2016) The regulation and functions of the nuclear RNA exosome complex. Nat Rev Mol Cell Biol 17, 227–239. 38 Andreu ...

Cell–Matrix Interactions Regulate Functional Extracellular Vesicle ...

Extracellular vesicles (EVs) are cell-secreted nanomaterials composed of a lipid bilayer that are conventionally described as ranging from 50 to ...

High frequency acoustic cell stimulation promotes exosome ... - OUCI

High frequency acoustic cell stimulation promotes exosome generation regulated by a calcium-dependent mechanism ... Authors: Lizebona August Ambattu; Shwathy ...

Techniques for increasing the yield of stem cell-derived exosomes

Exosomes are nano-scale extracellular vesicles secreted by cells and constitute an important part in the cell-cell communication.

Made by cells for cells – extracellular vesicles as next-generation ...

In summary, a unique and large library of miRNAs, proteins and mRNAs that are present in and on EVs can control and regulate osteogenesis by ...

Fig. 2 Formation of exosomes inside cell. Exosomes are nano-sized...

SNARE and Rab-GTPase (Rab11, Rab27, and Rab35) proteins facilitate the fusion of MVBs with the plasma membrane in order to release exosomes into extracellular ...

Regulation of chronic inflammatory and immune processes by ... - JCI

In addition, the fact that DCs and B cells increase the release of exosomes following cognate T cell interactions also suggests that EVs are ...

The Regulation of Exosome Secretion: a Novel Function of the p53 ...

... exosome production by cells was found to be regulated by the p53 response. A p53-regulated gene product, TSAP6, was shown to enhance exosome production in ...

Regulation of exosome production and cargo sorting

Almost all cells are capable for secreting various types of extracellular vesicles (EVs). In accordance with the origin, functions, and ...

Exosome - NGS Services (RNA Next Generation Sequencing)

More importantly, exosomal mRNA can be translated to proteins in receptor cells, and some exosomal miRNA can bind and regulate mRNAs of recipient cells.

Extracellular vesicles: new players in regulating vascular barrier ...

A variety of cells have been identified as parent cells capable of generating EVs, including platelets, leukocytes, endothelial cells, epithelial cells, ...

Cryptic unstable transcript

Cryptic unstable transcripts are a subset of non-coding RNAs that are produced from intergenic and intragenic regions. CUTs were first observed in S. cerevisiae yeast models and are found in most eukaryotes.