The prognostic impact of KRAS

Prognostic impact of KRAS mutant type and MET amplification in ...

FGFR2, EGFR, HER2, MET and KRAS gene amplification was suggested in 4.4%, 5.9%, 9%, 3.7% and 10.3% of patients, respectively. KRAS mutation, but not KRAS ...

Histology and its prognostic effect on KRAS‑mutated colorectal ...

The present study investigated the prognostic value of KRAS-mutation in CRCs and its association with histologic features.

The impact of KRAS mutations on prognosis in surgically resected ...

KRAS mutations are common in colorectal cancer (CRC). The role of KRAS mutation status as a prognostic factor remains controversial, ...

The prognostic impact of KRAS, TP53, STK11 and KEAP1 mutations ...

AbstractBackgroundPD-L1 expression is used to predict NSCLC response to ICIs, but its performance is suboptimal. The impact of KRAS mutations in these ...

The prognostic impact of KRAS, its codon and amino acid specific ...

The impact of common oncogenic driver mutations on prognosis in stage I NSCLC is limited. The pure prognostic value of KRAS mutational status ...

The Prognostic Role of KRAS Mutation in Patients with Advanced ...

Nevertheless, even after testing the effect of KRAS mutations from liquid biopsy. (to exclude tumor heterogeneity), unequivocal verification of predictive value ...

KRAS mutation is a weak, but valid predictor for poor prognosis and ...

Besides EGFR, KRAS is the most frequently mutated oncogene in NSCLC (15-20%) with most cases affect exon 2 and 3 (G12, G13 and Q61). It seemed ...

Clinical characteristics, outcomes and prognostic factors in KRAS ...

Conclusion: This is the largest dataset of KRAS mutant lung cancers from India. Brain metastases were higher in patients with G12C mutations and ...

Prognostic Impact of KRAS G12C Mutation in Patients With NSCLC

KRAS mutations, the most frequent gain-of-function alterations in NSCLC, are currently emerging as potential predictive therapeutic targets. The ...

[PDF] Not all mutations of KRAS predict poor prognosis in patients ...

The results support the concept that codon-12 mutations were predictive for a poor prognosis in Chinese patients with CRC and that G12D and G12V were ...

Prognostic and therapeutic impact of the KRAS G12C mutation in ...

This paper reviews the literature on KRAS G12C mutations, with a focus on the epidemiology and prognosis of KRAS G12C within CRC.

Prognostic Impact of KRAS Mutation Subtypes in 677 Patients with ...

To better under- stand the impact of KRAS mutation subtype, we analyzed data from. 677 patients with KRAS mutant metastatic lung cancer. Methods:We reviewed all ...

Prognostic Implication of KRAS G12C Mutation in a Real-World ...

From 28,120 registered patients with lung cancer, 1185 were selected with a KRAS mutation, of which 494 had a KRAS G12C mutation. Median OS was ...

Prognostic and Predictive Value of KRAS Mutations in Advanced ...

Clinical implications of KRAS mutations in advanced non-small cell lung cancer remain unclear. We retrospectively evaluated the prognostic and predictive ...

Prognostic Impact of KRAS G12C Mutation in Patients With NSCLC

Prognostic Impact of KRAS G12C Mutation in. Patients With NSCLC: Results From the European. Thoracic Oncology Platform Lungscape Project. Stephen P. Finn, MD,a ...

KRAS Status has Different Prognostic Impact on Initially Resectable ...

KRAS mutation status has been implicated in the prognosis of these patients. A new modified clinical risk score (m-CS), which includes this mutation and is ...

Prognostic value of KRAS and BRAF mutations in curatively ...

Prognostic effects of KRAS and BRAF mutations seem to be consistent across most strata of clinical variables, while the adverse effect of BRAF mutations on OS ...

Prognostic impact of KRAS mutant type and MET amplification in ...

Prognostic impact of KRAS mutant type and MET amplification in metastatic and recurrent gastric cancer patients treated with first-line S-1 ...

Impact of KRAS G12 mutations on survival with trifluridine/tipiracil ...

In metastatic colorectal cancer (mCRC), KRAS mutations are often associated with poorer survival; however, the prognostic impact of specific ...

Impact of KRAS and NRAS mutations on outcomes in acute myeloid ...

The clinical significance of RAS mutations remains poorly defined and prior studies have yielded conflicting results. We used causal inferential ...