Toward a new nosology of neurodegenerative diseases

Center for Alzheimer's and Neurodegenerative Diseases | BCM

Our mission is to dissect the unique interactions between genes, lifestyle and other factors that trigger Alzheimer's and other forms of neurodegeneration in ...

Molecular Pathological Classification of Neurodegenerative ...

Neurodegenerative diseases (NDDs) are characterized by selective dysfunction and loss of neurons associated with pathologically altered proteins that ...

Towards an improved early diagnosis of neurodegenerative diseases

Tissue accumulation of abnormal aggregates of amyloidogenic proteins such as prion protein, α-synuclein, and tau represents the hallmark of ...

Descriptive Epidemiology of Neurodegenerative Diseases

Descriptive epidemiology needs a new framework to update the area of neurodegenerative research, based on the advancement of both clinical and ...

Concerns with the new biological research criteria for synucleinopathy

We proposed alternatives, but also emphasised the need for advances in the neurodegeneration component of any biological classification. Finally, we agree with ...

Molecular pathology of neurodegenerative diseases: principles and ...

Neurodegenerative diseases are characterised by selective dysfunction and progressive loss of synapses and neurons associated with pathologically altered ...

Hallmarks of neurodegenerative diseases - Cell Press

Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural net- works. Nat. Neurosci. 13, 812–818. https ...

Pittsburgh Institute for Neurodegenerative Diseases

Diseases that are studied include Parkinson's disease, Amyotrophic Lateral Sclerosis (ALS), Huntington's Disease, Stroke and Alzheimer's Disease. The vision ...

Series Introduction: Neurodegeneration: What is it and where are we?

In practice, neurodegenerative diseases represent a large group of neurological disorders with heterogeneous clinical and pathological expressions affecting ...

Future Directions in Molecular Imaging of Neurodegenerative ...

Through the years, this approach to defining neurodegenerative diseases as a syndromal construct, and consequently to diagnosing them on the ...

"Neurodegenerative diseases remain an unsolved mystery"

Tzoulis' research focus is to understand the mechanisms underlying Parkinson's disease and develop new therapies. Working toward this goal ...

Neurodegenerative disease - Wikipedia

Biomedical research has revealed many similarities between these diseases at the subcellular level, including atypical protein assemblies (like proteinopathy) ...

DZNE About us > Overview

The common trait of the diseases researched by DZNE is “neurodegeneration”, a term that refers to a progressive decline and loss of neuron. Depending on which ...

Parkinson's: New three-type classification - healthcare-in-europe.com

... towards understanding and treating this complex and increasingly prevalent neurodegenerative disease. Current clinical classifications of PD ...

Genetics in Neurodegenerative Disorders: Modifying the Future

Neurodegenerative (NDG) illnesses, such as Alzheimer's disease and Parkinson's disease, are complex entities involving genetic, interactome, and environmental ...

Uncovering the Culprits of Neurodegenerative Disorders

Recent studies from Feinberg scientists have uncovered new insights into these disorders, elucidating the mechanisms behind Alzheimer's disease, Parkinson's ...

Revised Again: Alzheimer's Diagnostic Criteria Get Another Makeover

The draft criteria take into account recent discoveries about how biomarkers change over time, using them to stage disease. They retain amyloid ...

The quantitative analysis of neurodegenerative disease - Termedia

Three hypotheses have been proposed to describe neurodegenerative disease as a whole [8]. First, as a result of the complex interactions between ...

Neurodegenerative Disease - Physiopedia

Neurodegenerative diseases (NDD) are diverse conditions characterized by selective dysfunction and ongoing loss of neurons, glial cells and the neural ...

Parekh Center for Interdisciplinary Neurology - NYU Langone Health

These insights will provide new therapeutic approaches with wide applications across conditions such as Parkinson's disease, multiple sclerosis, and multiple ...