Tumor and immune reprogramming during immunotherapy in ...

The Role of Metabolic Reprogramming in the Tumor Immune ... - MDPI

Despite the efficacy of immunotherapy in treating HCC, the response rate remains unsatisfactory. Recently, research has focused on metabolic reprogramming and ...

Metabolic reprogramming of the immune response in the tumor ...

Overall, future studies need to consider how cancer cell metabolic pathways differ from activated lymphocytes in order to define a therapeutic window for cancer ...

Researchers develop a new way to safely boost immune cells to ...

... immune cells in the body and reprogramming them to attack and destroy cancer cells. This therapeutic method frequently uses cytokines, small ...

CAR T Cells: Engineering Immune Cells to Treat Cancer - NCI

And over the past decade, immunotherapy—therapies that enlist and strengthen the power of a patient's immune system to attack tumors—has rapidly ...

Reprogramming the Tumor Microenvironment to Improve ...

Emerging immunotherapeutic approaches have revolutionized the treatment of multiple malignancies. Immune checkpoint blockers (ICBs) have ...

Reprogramming the Tumor Immune Microenvironment Through ...

Cancer immunotherapy offers significant clinical benefits for patients with advanced or metastatic tumors.

Cellular reprogramming of cancer cells to antigen-presenting cells ...

Immunotherapy has transformed the treatment of cancers like advanced melanoma with immune checkpoint inhibitors. But not all cancers respond to immunotherapy, ...

Reprogramming of dendritic cells for cancer immunotherapy

Importantly, tumor-APCs were efficiently generated at the single cell level from primary cancer cells of 7 solid tumors that presented antigens ...

Strategies for Heating Up Cold Tumors to Boost Immunotherapies

Immune checkpoint inhibitors induce significant and durable treatment responses in about 20% of all cancers, but many patients have natural ...

Reprogramming the Brain Tumor Microenvironment to Enhance Anti ...

Achieving effective and sustainable anti-tumor immunity remains a significant challenge in cancer therapy, largely due to tumor ...

Flipping the script: reprogramming tumor cells into DCs

In conclusion, this research confirms the ability of PIB to reprogram tumor cells into cDC1s in vivo, allowing for immune-cold tumors to become ...

Immunotherapy for Kidney Cancer - Cancer Research Institute

Immunotherapy is a type of therapy that takes advantage of a person's own immune system to help kill cancer cells. The first indication that kidney cancer might ...

New Immunometabolic Strategy Based on Cell Type-Specific ... - MDPI

Tumor tissues are heterogeneous and influenced by metabolic reprogramming of the tumor immune microenvironment (TIME). In the TIME, multiple cell types interact ...

Advances in macrophage and T cell metabolic reprogramming and ...

Macrophages and T cells in the tumor microenvironment (TME) play an important role in tumorigenesis and progression.

Engineering Nanoparticles to Reprogram the Tumor Immune ...

However, it does not work well in large patient populations because of an immunosuppressed microenvironment and limited reinvigoration of antitumor immunity.

Tumor-Homing and Immune-Reprogramming Cellular Nanovesicles ...

Despite advances in surgery, radiotherapy, chemotherapy, and phototherapy, cancer remains a significant public health problem worldwide and a ...

Immune reprogramming via PD-1 inhibition enhances early-stage ...

Success of immune checkpoint inhibitors in advanced non-small-cell lung cancer (NSCLC) has invigorated their use in the neoadjuvant setting ...

Reprogramming a brain tumor's immune response against itself

The immune landscape in glioblastoma differs from other types of cancers, rendering current immune checkpoint blockade ineffective at ...

Targeting Cellular Mechanisms of the Tumor Immune Response

... immune cells within it is critical to developing more effective cancer therapies. In particular, immunotherapies that target the signaling ...

What is Immunotherapy? - Dana-Farber Cancer Institute

Immunotherapy refers to treatments that use the body's own immune system to combat diseases; immuno-oncology specifically involves immunotherapy directed at ...