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human platelet antigens


Genetic variants of human platelet antigens in the Indian population ...

Abstract. Background Genetic variants in human platelet antigens (HPAs) considered as allo- or auto antigens are associated with various ...

Natural course of pregnancies with alloantibodies against human ...

Aims: To assess the incidence of clinically detectable severe foetal and neonatal alloimmune thrombocytopenia (FNAIT) among human platelet antigen-1a (HPA-1a) ...

500314: HPA-1a (PLA1 Platelet Antigen) Genotyping ... - Labcorp

Nomenclature of human platelet alloantigens: A problem with the HPA system? Blood. 1994; 83(6):1447-1451. Nugent DJ. Alloimmunization to platelet antigens.

Polymorphisms of the Human Platelet Antigens HPA-1, HPA-2, HPA ...

Polymorphisms of the Human Platelet Antigens HPA-1, HPA-2, HPA-3, and HPA-5 on the Platelet Receptors for Fibrinogen (GPIIb/IIIa), von Willebrand Factor ...

Human platelet antigens polymorphisms: Association to primary ...

Background: Human platelet antigens (HPAs) are part of platelet GP complexes have the potential to contribute to the autoantibody production ...

Platelet Antigen Identification | HPA BeadChip - Immucor

HPA BeadChip is a high-throughput m olecular assay that detects 22 human platelet antigens by multiplex DNA analysis.

Human Platelet Antigen Genotyping and Diagnosis of Antiplatelet ...

Rapid genotyping of human platelets can improve the diagnosis and treatment of neonatal alloimmune thrombocytopenia and minimize the risks ...

Progress and development of platelet antibody detection

Monoclonal antibody immobilization of platelet antigens assay (MAIPA). A panel of platelets carrying different HPA typed glycoproteins are incubated with human ...

Genetic polymorphisms of human platelet antigens-1 to -6, and

Human platelet antigens (HPA) are determinant in several platelet-specific alloimmune disorders, such as neonatal alloimmune thrombocytopenia, post-transfusion ...

Human platelet antigens in disease. - Abstract - Europe PMC

Platelets have various functions and participate in primary hemostasis, inflammation, and immune responses. Human platelet antigens (HPAs) are alloantigens ...

HPA Gene Database - Versiti

Human Platelet Antigen (HPA) Database. The database provides a centralized repository for discovered and known human platelet antigens. Review Database ...

Disequilibrium of Human Platelet Antigen 1 (HPA-1) in U.S. Population

Alloimmunization against Human Platelet Antigens (HPA) is associated with Neonatal Alloimmune Thrombocytopenia (NAIT), post-transfusion purpura and ...

Laboratory testing for the diagnosis of immune-mediated ...

In addition to ABO blood group type antigens and human leukocyte antigen (HLA) class I, which are non-platelet specific antigens, human platelets also express ...

Low-frequency human platelet antigens as triggers for neonatal ...

LFHPAs were identified in 27 of 1338 maternal samples (2.01%). HPA-9bw was by far the most common LFHPA identified in the populations studied ...

Simultaneous genotyping for human platelet antigen systems and ...

In order to treat the alloimmunization platelet transfusion refractoriness (PTR), human leukocyte antigen (HLA)-type and/or human platelet ...

Human platelet antigens 2013 - CiteSeerX

In addition to the HPA markers, platelets also express ABO and human leucocyte antigen (HLA) antigens; antibodies directed at the former are ...

1bb alloimmunized with fetal HPA-1a - Archives of Medical Science

Introduction: Pregnant women negative for human platelet antigen 1a (HPA-1a) are at risk of alloimmunization with fetal HPA-1a antigen inherited from the father ...

Genotyping of Eight Human Platelet Antigen Systems in Serbian ...

The aim of this study was to investigate the allele and genotype frequencies of 8 human platelet antigen (HPA) systems among blood donors from the Blood ...

Human platelet antigens and primary immune thrombocytopenia

Primary immune thrombocytopenic purpura (ITP) is an acquired immune-mediated disorder characterized by tran- sient or persistent decreased platelet count ...