A Phase II Randomized Study Evaluating the Biological and Clinical ...

Efficacy of Perioperative Chemotherapy for Resectable Pancreatic ...

Findings In this randomized phase 2 clinical trial, perioperative chemotherapy with either regimen led to a 2-year OS of about 47% (median OS of ...

A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to ...

Primary Objectives: To assess the efficacy of lademirsen (SAR339375) in reducing the decline in renal function.To assess the safety and ...

Phases of clinical trials - Cancer Research UK

Clinical trials are divided into different phases. Most trials are phase 1, 2 or 3. But some trials are classified as phase 0 and some as ...

A randomized phase 2 trial of azacitidine with or without durvalumab ...

A randomized phase 2 trial of azacitidine with or without durvalumab as first-line therapy for older patients with AML. Clinical Trials & ...

Release Details - Candel Therapeutics

Candel has established two clinical stage multimodal biological ... This randomized, open-label phase 2 clinical trial is designed to evaluate ...

A randomized, placebo-controlled, phase II study of obeticholic acid ...

This phase II study evaluated OCA in patients with PSC. •. OCA 5–10 ... In phase II and III clinical studies in patients with PBC ...

The MENDEL-2 Randomized, Controlled Phase III Clinical Trial of ...

3). Evolocumab treatment in the biweekly and monthly groups led to LDL-C decreases of >50% in 75.7% and 78.7% of patients when evaluated by LDL ...

Immuno-PRISM: A Randomized Phase II Platform Study of Bispecific ...

Research, clinical trials, Biological therapies, adult, Bispecific Antibody Therapy, Clinical ... II, platform study evaluating TEC vs ...

FLAIR: A Phase II, Open Label, Randomized Study of Osimertinib ...

Although the 2 common EGFR mutations, 19Del and L858R mutation, could predict clinical benefits from EGFR-TKIs, possible differential ...

A Phase IIB Randomized Study of Oral Seliciclib in Patients with ...

A phase 2 study to evaluate efficacy of oral seliciclib in treating non-small cell lung cancer (NSCLC).

Biomarker-directed targeted therapy plus durvalumab in advanced ...

Here the phase 2 umbrella HUDSON study evaluated rational ... randomized phase 2 POPLAR and phase 3 OAK clinical trials. J. Thorac ...

The Results of a Phase II Randomized Trial Comparing 5 ...

Only in patients with a clinical suggestion of early progression of disease was radiographic evaluation performed before completion of 2 full courses of ...

A Phase 2 Randomized Trial Evaluating the Antiviral Activity and ...

2020. Assessing COVID-19-related symptoms in outpatient adult and adolescent subjects in clinical trials of drugs and biological products for ...

Clinical Trials at UMMC - University of Mississippi Medical Center

However, we cannot do it alone. Clinical research studies are vital to the advancement of medicine and our vision to create "a healthier ...

A simplified guide to randomized controlled trials - Bhide - 2018

Clinical trials evaluating safety and efficacy of pharmaceutical ... Phase II trials are designed to estimate dose and test the safety ...

A review of phase 2–3 clinical trial designs - Biostatistics

Phase3 trials are considered the most scientifically reliable tool for confirmatory evaluation of new treatments. In phase3, patients are ...

Protocol Search - NRG Oncology

A Phase III Clinical Trial evaluating De-escalation of Breast Radiation ... A Randomized Phase II/III Study to Assess the Efficacy of Trametinib (GSK ...

Clinical Trials - Cleveland Clinic

A Phase 2, Open-label Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in ...

A Phase II Randomized Controlled Trial of Genomically Directed ...

This includes evaluation of tens of thousands of genomic abnormalities, driver mutations, and changes associated with clinical trials. This panel has a near- ...

Evaluation of phase II clinical trials of small molecule targeted ...

14686 Background: Small molecule inhibitors, often cytostatic, pose challenges to phase (ph) II trial paradigms. Randomized ph II studies assessing rates ...