Biomarkers of acute kidney injury

Acute kidney injury | Nature Reviews Disease Primers

New biomarkers to identify injury before function loss await clinical implementation. AKI and AKD are a global concern. In low-income and middle ...

Biomarkers in acute kidney injury: Evidence or paradigm? | Nefrología

The 90kDa soluble ectodomain is part of the dependent metalloproteinase complexes and it is released into the tubule by epithelial cells making it readily ...

Investigational biomarkers and the evaluation of acute kidney injury

Acute kidney injury (AKI) is a common clinical problem [1-7]. Although measurement of the serum creatinine concentration is widely used for the ...

Biomarkers Consortium – Clinical Evaluation and Qualification of ...

These studies seek to confirm the predictive validity of this set of urine biomarkers that reliably change in response to AKI prior to irreversible kidney ...

Comparative accuracy of biomarkers for the prediction of hospital ...

Several biomarkers have been proposed to predict the occurrence of acute kidney injury (AKI); however, their efficacy varies between ...

Roadmap for Accelerating the Development of Biomarkers for Acute ...

The community defines and evaluates acute kidney injury (AKI) based on changes in functional biomarkers (i.e., serum creatinine. [sCr] or urine output) that do ...

Novel biomarkers of acute kidney injury: Evaluation and evidence in ...

SCr remains the mainstay for evaluation of kidney function in urologic surgical patients. However, novel biomarkers may complement SCr measurement to indicate ...

Update on Biomarkers of Acute Kidney Injury

The most promising AKI biomarkers include plasma and urinary neutrophil gelatinase-associated lipocalin (NGAL), urinary interleukin (IL)-18, ...

Biomarkers of Acute Kidney Injury in Chronic Heart Failure

Given that acute decompensated heart failure is the setting for the majority of these studies, where an increase in serum creatinine may very well represent ...

Biomarkers of Acute Kidney Injury

The diagnosis of acute kidney injury (AKI) is usually based on measurements of blood urea nitrogen. (BUN) and serum creatinine. BUN and serum creatinine are ...

New kidney biomarkers: A faster way to detect acute kidney injury

These tests detect biomarkers in the blood or urine, signaling the patient is likely to experience AKI or is already experiencing it.

Kidney-specific biomarkers for predicting acute kidney injury ...

1. ... 2. ... Cardiac arrest is associated with multiple organ dysfunction. ... 3. ... 4. ... Acute kidney injury (AKI) is seen in approximately 50% of ...

Combination of Two Urinary Biomarkers Predicts Acute Kidney ...

When urinary L-FABP and NAG are combined, they can detect AKI adequately, even in a heterogeneous population of adult post-cardiac surgery AKI. Combining 2 ...

Education -- Biomarkers of kidney disease: potential utilities

Early diagnosis of kidney injury · Screening patients at risk for acute kidney injury · Differentiating upper and lower urinary tract infection · Markers of ...

Novel predictive biomarkers for acute injury superimposed on ...

Our study revealed the variational expression of AKI biomarkers in AonC kidneys, and uncovered IGFBP7 protein can be used as a sensitive biomarker to predict ...

Biomarkers Identify Acute Kidney Injury in Emergency Patients

Although all five biomarkers were elevated in cases of iAKI (intrinsic AKI, the most severe form of AKI), the biomarker called uNGAL was most ...

Novel Biomarkers to Anticipate Acute Kidney Injury. Getting Ahead ...

The urinary [TIMP-2]·[IGFBP7] biomarker panel appears to have excellent predictive capacity for near-time diagnosis of AKI and, in theory, should logically now ...

Machine Learning in Diagnosing Acute Kidney Injury

Accompanying this increasing emphasis on identifying patients at a high risk for AKI was the search for novel urinary and serum biomarkers for the diagnosis of ...

Urinary biomarkers for acute kidney injury: Perspectives on translation

The major types of urinary biomarkers fall into three classes: (1) Inflammatory, (2) renal tubular proteins that are excreted into the urine after injury, and ( ...

Which Marker Should We Use to Assess Acute Renal Injury

New Biomarkers for AKI ... Neutrophil gelatinase-associated lipocalin (NGAL) has been extensively studied as a potential biomarker for AKI. NGAL, ...