Cancer Genome Sequencing

... Cancer is an international leader in genomics, proteomics and bioinformatics for precision medicine. By developing and deploying cutting-edge genome sequencing ...

UCSF 500 Cancer Gene Panel Test (UCSF500 / UC500)

The UCSF 500 Cancer Gene Test uses capture-based next-generation sequencing to target and analyze the coding regions (exons) of 529 cancer genes, as well as ...

Perlmutter Cancer Center Genomics Expert Expands Clinical ...

Dr. Imieliński's research focuses on cancer whole-genome sequencing, particularly in developing new algorithms for analyzing cancer whole genomes.

Racial disparities discovered among genomic sequencing data

Mayo Clinic researchers have found gaps in the genomic data included in The Cancer Genome Atlas. This is one of the first steps toward ...

Diagnostic Cancer Genome Sequencing and the Contribution of ...

We also address challenges in the clinical implementation of the variants in germline DNA identified through cancer genome sequencing. We ...

New DNA Sequencing Method May Lead to Earlier Cancer Detection

The technique, created by Penn Medicine researchers, requires smaller DNA samples for testing and opens up potential new opportunities for next-generation ...

Genome Sequencing Facility (GSF)

The Genome Sequencing Facility (GSF) was created in 2011 by Greehey Children's Cancer Research Institute (Greehey CCRI) in UT Health San Antonio, upon the ...

Optimizing Cancer Genome Sequencing and Analysis: Cell Systems

Tumors are typically sequenced to depths of 75x–100x (exome) or 30x–50x (whole genome). We demonstrate that current sequencing paradigms are inadequate for ...

MSK-IMPACT: A Targeted Test for Mutations in Both Rare and ...

A notable feature of MSK-IMPACT is that two DNA samples from each person are sequenced and compared: DNA from tumor tissue and from normal tissue. The normal ...

Cancer Genomics & Bioinformatics Core - Jefferson Research

A centralized resource with a full array of services from Sanger sequencing, genotyping, gene expression analysis to next-generation sequencing.

Racial/Ethnic Disparities in Genomic Sequencing - JAMA Network

Objective To determine the racial distribution among samples sequenced within The Cancer Genome Atlas (TCGA) and the deficit of samples needed ...

Comprehensive analysis of microbial content in whole-genome ...

Here we have expanded our analysis to cover all 5,734 whole-genome sequencing (WGS) data sets currently available from The Cancer Genome Atlas ( ...

The Status and Impact of Clinical Tumor Genome Sequencing

Annual Review of Genomics and Human Genetics, Volume 20, 2019, The Status and Impact of Clinical Tumor Genome Sequencing

Whole Cancer Genome Sequencing by Next-Generation Methods

Abstract. Traditional approaches to sequence analysis are widely used to guide therapy for patients with lung and colorectal cancer and for patients with m.

Sequencing cancer genomes to tailor treatments to individual patients

Screening for hundreds of mutations in tumours is the most promising route to customised drug treatments for cancer.

Cancer Genome Sequencing—An Interim Analysis - AACR Journals

The first complete sequencing of all likely coding exons of a human cancer genome, conducted in breast and colon cancers (8, 9), concluded that ...

Whole-genome sequencing of phenotypically distinct inflammatory ...

Inflammatory breast cancer (IBC) has a highly invasive and metastatic phenotype. However, little is known about its genetic drivers.

Why whole genome sequencing can improve child cancer treatments

NHS England already offers whole genome sequencing for any child diagnosed with cancer, but it's not routinely used by most hospitals.

Genome sequencing helps prioritize cancer treatment options

POG employs whole genome sequencing to analyze both the inherited and the cancer genomes of individual patients. In a new study published in ...

Kidney Cancer Genome Sequencing - Research - Brugarolas Lab

Technology now allows us to “read” the entire sequence of bases that makes up the DNA or human genome. By comparing the sequence of healthy tissue and tumors, ...