Discovery of genomic variation across a generation

Discover a new generation of molecular sensing technology which offers short to ultra-long native DNA and RNA reads.

Dating genomic variants and shared ancestry in population-scale ...

Each generation, a human genome acquires an average of about 70 single-nucleotide changes through mutation in the germline of its parents [1]. Yet while, at a ...

A map of human genome variation from population-scale sequencing

These resources have driven disease gene discovery in the first generation of genome-wide association studies (GWAS), wherein genotypes at ...

Human Genome Variation Society

Members of the Society have published a number of papers in relation to human genome variation and in particular mutation databases. The Society maintains a ...

Ten years of variant discovery in the 1000 Genomes Project (2021)

Experts from across the Broad Institute community give in ... Next Generation Sequencing 1: Overview - Eric Chow (UCSF). iBiology ...

BRCA Gene Changes: Cancer Risk and Genetic Testing Fact Sheet

People can also have germline genetic testing on their own, through ... Cancer Discovery 2015; 5(2):135–142. [PubMed Abstract]. Rebbeck TR ...

UCSC Genome Browser Gateway

To address this, the GRCh38 assembly provides alternate sequence for selected variant regions through the inclusion of alternate loci scaffolds (or alt loci).

VarSome The Human Genomics Community

VarSome is a variant knowledge community, data aggregator and variant data discovery tool.

Genome Variation Map

The Genome Variation Map (GVM) is a public data repository of genome variations, including single nucleotide polymorphisms and small insertions and deletions.

Deep history within the human genome - YouTube

Comments45 · Evolution of human genes and the origin of agriculture · Ancient genomes 2: Neandertals within us · Ancient genomes 1: The Denisovans.

COSMIC | Catalogue of Somatic Mutations in Cancer

Mutation profiles of over 1,000 cell lines used in cancer research; COSMIC-3D ... Cancer Mutation Census Classification of genetic variants driving cancer ...

DNA Sequencing Market to Grow by USD 17.34 Billion (2024-2028 ...

... genetic variation in clinical diagnosis and drug discovery. Next-Generation Sequencing (NGS) technologies, including Whole-Genome Sequencing ...

1000 Genomes Project: Defining Genetic Variation in People

November 2012 - An international team of researchers working on the 1000 Genomes Project published in Nature on Nov.

Whole Genome and Exome Sequencing Markets, 2033

In the pharmaceutical industry, whole genome and exome sequencing have been pivotal in drug discovery and development, allowing for the ...

DNA Sequencing Market to Grow by USD 17.34 Billion (2024-2028 ...

Next-Generation Sequencing (NGS) technologies, including Whole-Genome Sequencing (WGS), have revolutionized the field of genomics, enabling the ...

GTEx Portal

... gene expression and regulation across individuals, development, and species, with data from 3 NIH projects. The Adult GTEx project is a comprehensive ...

The role of epigenetics in phenotypic evolution

These systems may serve as a basis for understanding the genome biology in higher eukaryotes. Despite extensive discoveries made about the ...

Whole Genome and Exome Sequencing Market Research 2024-2033

In the pharmaceutical industry, whole genome and exome sequencing have been pivotal in drug discovery and development, allowing for the ...

Bratati - CBR - Centre for Brain Research

As a computational biologist focusing on human genetics and genomics, her research broadly examines the role of genetic variants in shaping our inherited traits ...

Molecular Mechanisms of Heterosis and Its Applications in Tree ...

Building on this, CRISPR-based gene-editing technologies can be employed to precisely edit heterotic loci, enabling the study of allele function. Additionally, ...