Eeyarestatin Compounds Selectively Enhance Sec61|Mediated ...

Combining Valosin-containing Protein (VCP) Inhibition and ...

Results: VCP inhibition using Eeyarestatin I reduces the ERAD of ␣1(A322D) subunits, and coapplication of SAHA additively enhances their ...

Small molecules for impairing endoplasmic reticulum in cancer

4)-mediated HSP90 inhibition triggered ER stress by increasing the expression of GRP78 and GRP94, caspase-12 cleavage, and upregulation of ...

Sec61 blockade by mycolactone inhibits antigen cross-presentation ...

To prime relevant T cells, DCs capture antigens released by the surrounding cells and present them in the context of MHC class I (MHC-I) molecules (2). This ...

Eeyarestatin 1 Interferes with Both Retrograde and Anterograde ...

... compounds were present throughout the toxin challenge ... (2009) Eeyarestatin I inhibits Sec61-mediated protein translocation at the endoplasmic reticulum.

The exploitation of mannosyltransferase inhibitors to modulate ... - GtR

Gamayun I (2019) Eeyarestatin Compounds Selectively Enhance Sec61-Mediated Ca2+ Leakage from the Endoplasmic Reticulum. in Cell chemical biology. publication ...

Pharmacological Modulation of Ca2+ Leak through Sec61 ... - CORE

time between applications of eeyarestatin compounds and thapsigargin application none ... selectively enhance Sec61-mediated Ca. 2+ leak from the endoplasmic ...

Sec61 Inhibitor Apratoxin S4 Potently Inhibits SARS-CoV-2 and ...

Eeyarestatin compounds selectively enhance Sec61- mediated Ca2+ leakage from the endoplasmic reticulum. Cell Chem. Biol. 2019, 26 (4), 571 ...

Inhibition of protein translocation at the endoplasmic reticulum ...

The small molecules ESI (eeyarestatin ... M. R.. , et al. Eeyarestatin I inhibits Sec61-mediated protein translocation at the endoplasmic ...

ERAD inhibitors integrate ER stress with an epigenetic mechanism ...

Here we report that Eeyarestatin I (EerI), a chemical inhibitor that ... enhancing Noxa-mediated activation of Bak. Blood 109, 4441 ...

Inhibition of protein translocation at the endoplasmic reticulum ...

... Eeyarestatin Compounds Selectively Enhance Sec61-Mediated Ca2+ Leakage from the Endoplasmic Reticulum. Gamayun I., O'Keefe S., Pick T., Klein ...

Eeyarestatin 1 (CAS Number: 412960-54-4) | Cayman Chemical

The ERAD inhibitor Eeyarestatin I is a bifunctional compound with a membrane-binding domain and a p97/VCP inhibitory group. PLoS One 5(11), 1-12 (2010). 4.

Eeyarestatin I | ERAD Inhibitor - MedchemExpress.com

Eeyarestatin I inhibits Sec61 translocon. Eeyarestatin I targets the p97-associated deubiquitinating process (PAD) and inhibits atx3-dependent deubiquitination.

Eeyarestatin I | ES1 | ERAD inhibitor | Axon 1798

Eeyarestatin I inhibits Sec61-mediated protein translocation at the endoplasmic reticulum. ... Selective inhibitor of LMP7 subunit of the immunoproteasome.

Eeyarestatin I | ≥99%(HPLC) | Selleck | その他阻害剤

Eeyarestatin I is a potent inhibitor of endoplasmic reticulum-associated protein degradation (ERAD). Eeyarestatin I also inhibits Sec61 translocon.

8DO3: Cryo-EM structure of the human Sec61 complex inhibited by ...

Cryo-EM structure of the human Sec61 complex inhibited by eeyarestatin I · A common mechanism of Sec61 translocon inhibition by small molecules.

Eeyarestatin I - APExBIO

Eeyarestatin I inhibits Sec61-mediated protein translocation at the endoplasmic reticulum. ... Eeyarestatin I Is a Bifunctional Compound with a Membrane ...

Eeyarestatin I | CAS 412960-54-4 | SCBT - Santa Cruz Biotechnology

Eeyarestatin I, CAS: 412960-54-4, is a potent inhibitor of endoplasmic reticulum associated protein degradation. Cited in 12 publications.