- Dissection of the Dislocation Pathway for Type I Membrane Proteins ...🔍
- Inhibition of protein translocation at the endoplasmic reticulum ...🔍
- Covalent inhibition of endoplasmic reticulum chaperone GRP78 ...🔍
- Inhibition of apolipoprotein B100 secretion by lipid|induced hepatic ...🔍
- Pathogenic proteotoxicity of cryptic splicing is alleviated by ...🔍
- The Human Protein Atlas🔍
- Harnessing Cuproptosis🔍
- “ER|associated autophagy”🔍
Inhibition of endoplasmic reticulum associated degradation reduces ...
Dissection of the Dislocation Pathway for Type I Membrane Proteins ...
The mammalian endoplasmic reticulum (ER)-to-cytosol degradation pathway for disposal of misfolded proteins is an attractive target for therapeutic ...
Inhibition of protein translocation at the endoplasmic reticulum ...
ESI induces mislocalization and degradation of membrane and secretory proteins in ...
Covalent inhibition of endoplasmic reticulum chaperone GRP78 ...
Celastrol covalently inhibited the chaperone activity of GRP78 and could disconnect the transduction of ER stress signal to downstream ...
Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic ...
This decreased secretion at higher lipid levels was due to increased protein degradation through both proteasomal and nonproteasomal pathways and was dependent ...
Beta cells are sensitive to blood sugar levels so that they secrete insulin into the blood in response to high level of glucose, and inhibit secretion of ...
Pathogenic proteotoxicity of cryptic splicing is alleviated by ... - Science
... endoplasmic reticulum stress and proteotoxic aggregates. Enhancing protein degradation systems such as the ubiquitin-proteasome system and ...
The atlas for all human proteins in cells and tissues using various omics: antibody-based imaging, transcriptomics, MS-based proteomics, and systems biology ...
Sulfatide is synthesized primarily starting in the endoplasmic reticulum and ... Sulfatide has also been shown to be an inhibitor of myelin-associated ...
Harnessing Cuproptosis: A Novel Bioinformatics and Machine ...
To investigate the role of cuproptosis-related genes in renal ischemia-reperfusion injury and establish a robust diagnostic model.
“ER-associated autophagy”: a new pathway to degrade misfolded ...
Watch this 2-minute video abstract for a quick look into the publication: "Lysosome Docking to WIPI1 Rings and ER-connected Phagophores ...
Neuroprotective effects of green coffee bean extract ... - Food and Life
Coffee consumption is associated with reduced ... Chlorogenic acid exerts beneficial effects in 6-hydroxydopamine-induced neurotoxicity by inhibition of ...
Glucosamina: MedlinePlus suplementos
Phase II study of glucosamine with chondroitin on aromatase inhibitor-associated ... Glucosamine-induced endoplasmic reticulum stress attenuates apolipoprotein ...
Denali Has A Neurodegenerative Edge Despite Market Skepticism
By inhibiting LRRK2 kinase activity, which in turn modifies neuronal degradation ... Motor neuron death due to chronic endoplasmic reticulum ...
When binocular performance is lower than monocular performance, binocular inhibition takes place. ... degradation. The amblyopic eye abruptly becomes the ...
Glycocalyx - Definition, Composition, Types, Functions.
Cell adhesion: It held cells together so that tissues do not fall apart. What is Biofilm? Biofilms are the complex bacterial communities of pathogenic bacteria, ...
Vesicles - Definition, Structure, Types, and Functions
Numerous vesicles are produced in the Golgi apparatus and endoplasmic reticulum or by endocytosis from portions of the cell membrane. ... degradation of molecules ...