Statistical models for biphasic dose|response relationships ...

Biphasic dose responses in biology, toxicology and medicine

Hormetic dose response relationships represent an estimate of the peak performance of integrative biological processes that are allometrically ...

Dose-Response-Time Data Analysis - Pharmacological Reviews

and Jonsson EN (2010) A pharmacometric model describing the relationship be- tween warfarin dose and INR response with respect to variations in CYP2C9,.

A Theoretical Model for the Hormetic Dose-response Curve for ...

We hypothesize that anticancer agents possess a bi-phasic sigmoidal dose response relationship consisting of hormetic and cytotoxic effects.

Dose-Response Analysis Using R - CORE

So we define dose-response models to be a collection of statistical models having a certain ... relationship at all, i.e., comparing the dose- ...

Therapeutic Efficacy of Endostatin Exhibits a Biphasic Dose ...

In tumor-bearing animals, there is a similar biphasic effect on the inhibition of tumor growth and on circulating endothelial cells after once-daily s.c. ...

Hormesis: Biphasic Dose-Responses to Fungicides in Plant ...

A parametric model is an equation with a finite number of parameters that describe the relationship between two variables, in the case of ...

Hormesis - Wikipedia

In the context of toxicology, the hormesis model of dose response is vigorously debated. ... The biochemical mechanisms by which hormesis works (particularly in ...

Comparing Two Statistical Models for Low Boom Dose-response ...

On the other hand, a population average model utilizes generalized estimating equations and accounts for the correlation via a user-specified ...

The Biphasic Dose-Response Curve in Photobiomodulation

The biphasic dose-response curve is often illustrated as a U-shaped or bell-shaped curve, representing how both insufficient and excessive doses result in ...

Late onset pancytopenia post chimeric antigen receptor T cell ...

Diagnosed in 2019, she was initially treated in the UKALL60+ trial with a very good MRD response. ... relationships that could be construed as a potential ...

6. DOSE-RESPONSE MODELLING

The Poisson distribution is generally used to characterize the variability of the individual doses when pathogens are randomly distributed. Microorganisms have ...