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The Unfolded Protein Response and Autophagy on the Crossroads ...


Understanding the Unfolded Protein Response (UPR) Pathway

Additionally, IRE1α's interactions with adapter proteins facilitate various stress response pathways, including macroautophagy and the MAPK pathway, ...

Autophagy counterbalances endoplasmic reticulum expansion ...

The protein folding capacity of the endoplasmic reticulum (ER) is regulated by the unfolded protein response (UPR). The UPR senses unfolded proteins in the ...