Transcriptome Profiling of Prostate Cancer

Integrated single-cell transcriptomic analyses identify a novel ...

In prostate cancer (PCa), lineage plasticity often results in therapy resistance and trans-differentiation to neuroendocrine (NE) lineage. However, identifying ...

Dynamic prostate cancer transcriptome analysis delineates ... - OUCI

AbstractComprehensive genomic studies have delineated key driver mutations linked to disease progression for most cancers.

Liquid-biopsy transcriptomic profiling uncovers molecular ... - medRxiv

Prostate cancer is a highly heterogeneous disease driven by androgen receptor (AR) signaling. Despite initial androgen deprivation therapy, most ...

Combining machine learning and reference-free transcriptome ...

Using this pipeline, we were able to produce new diagnostic and prognostic signatures for prostate cancer. These "reference-free" signatures do ...

Multi‐omic profiling reveals an RNA processing rheostat that ...

Prostate cancer is the most commonly diagnosed malignancy and the third leading cause of cancer deaths. GWAS have identified variants ...

ASCO GU 2020: Transcriptome Profiling of NRG Oncology/RTOG ...

... Prostate Cancer from a Prospective Randomized Trial. San Francisco, CA (UroToday.com) RTOG 9601 was a double-blind, placebo-controlled trial ...

Identification of a candidate prognostic gene signature by ...

We performed in vivo transcriptome profiling of pre- and post-treatment prostatic biopsies from patients with advanced hormone-naive prostate ...

Pan-cancer transcriptome analysis reveals a gene expression ...

An overall accuracy of 92% was achieved on the 1248 tumor specimens that were poorly differentiated, undifferentiated or from metastatic tumors. Thus, we have ...

Transcriptome analysis identifies networks and key drivers in tumor ...

Transcriptome analysis identifies networks and key drivers in tumor microenvironment for metastatic castration-resistant prostate cancer.

Determination of tag density required for digital transcriptome analysis

In this report, we attempted to address these issues on an androgen-sensitive prostate cancer cell model. Using a double- random priming ...

Isolate RNA for Global Transcriptome Analysis - ES

As with many cancers, the molecular underpinnings of prostate cancer (PrCa) are poorly defined. Animal models, such as xenograft mice, offer an invaluable, ...

Transcriptomic heterogeneity in multifocal prostate cancer.

Given heterogeneity and multifocality of primary prostate cancer, such assays should ideally be robust to the coexistence of unsampled higher grade disease ...

Prediction of Clinically Significant Prostate Cancer by a Specific ...

Transcriptome analysis was performed using R v4.2.3 as described in the Supplementary material. Six publicly available transcriptome data sets ...

Molecular profiling in prostate cancer: key challenges for clinical ...

He initially talks about the unmet needs in prostate cancer management. He expands on genomic DNA testing, transcriptome RNA profiling ...

Transcriptome profiling of cancer and normal tissues from cervical ...

The present study reported transcriptome sequencing analysis of three cervical squamous cell cancer tissues and paired normal cervical tissues.

Integrative transcriptome analysis identifies genes and pathways ...

We searched Gene Expression Omibus (GEO) for all enzalutamide-related mRNA expression studies that were performed on prostate cancer cell lines. We selected and ...

A comparative assessment of clinical whole exome and ... - Oncotarget

... transcriptome profiling across sequencing centers: implications for precision cancer medicine ... prostate cancer across sequencing centers ...

spatial transcriptome analysis reveals the tumor heterogeneity and ...

Ductal adenocarcinoma is a rare subtype of prostate cancer with unknown pathogenesis and poor prognosis. While some studies have investigated the genetic ...

Isolate RNA for Global Transcriptome Analysis - ID

As with many cancers, the molecular underpinnings of prostate cancer (PrCa) are poorly defined. Animal models, such as xenograft mice, offer an invaluable, ...

The Cancer Genome Atlas Program (TCGA) - NCI

The Cancer Genome Atlas (TCGA) is a landmark cancer genomics program that sequenced and molecularly characterized over 11000 cases of primary cancer samples ...