Clinical implications of opioid|induced ventilatory impairment

Opioid-induced respiratory depression - BJA Education

∙ Gershuny, V. ... Effect of paroxetine or quetiapine combined with oxycodone vs oxycodone alone on ventilation during hypercapnia: a randomized ...

The effect of esketamine on the hypoxic ventilatory response

While we know that opioids are potent respiratory depressants, including depression of the hypoxic ventilatory response (HVR; the increase in breathing caused ...

Role of the nurse in supporting the safe use of opioids - RCNi

... effects need to be managed. For example, mild opioid-induced ventilatory impairment may not warrant aggressive treatment in a person at the ...

Adult guidelines for Naloxone Use

Opioid Induced Ventilatory Impairment (OIVI) ... Therefore close patient monitoring is required, as repeat doses may be needed to maintain the clinical effect.

Opioid Analgesics and the Gastrointestinal Tract

Drug-drug interactions and end organ dysfunction may exacerbate systemic side effects of these drugs. In patients who have failed to respond to these agents, ...

Chronic opioid use - Royal College of Physicians of Edinburgh

of sleep-disordered breathing secondary to impaired central respiratory drive. KEYWORDS Opioids, adaptive servo-ventilation, central sleep apnoea.

Oxygen-induced hypercapnia: physiological mechanisms and ...

The effect of high concentration ... Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure.

Postoperative Patients Statement

There is evidence that the use of modified release opioids after surgery can lead to harm for patients 1. Adverse effects such as opioid induced ventilatory ...

Neuronal mechanisms underlying opioid-induced respiratory ...

However, when opioids are administered locally into this region in vivo, effects on ventilation have been shown to be variable, resulting in either a decrease, ...

Predicting opioid-induced oversedation in hospitalised patients

Objectives Opioid-induced respiratory depression (OIRD) and oversedation are rare but potentially devastating adverse events in hospitalised patients. · Design ...

Safe use of opioids measurement Frequently asked questions

patient? Opioid induced ventilatory impairment (OIVI) is difficult to predict. A meta-analysis by Overdyke et al33 demonstrated that only 30 ...

Opioid Complications and Side Effects - :::::Pain Physician:::::

Physical dependence and addiction are clinical concerns that may prevent proper prescribing and in turn inadequate pain management. Less common side effects may ...

The influence of drugs used for sedation during mechanical ...

Assessing breathing effort in mechanical ventilation: physiology · and clinical implications. ... Fentanyl-induced · respiratory depression is ...

Diaphragm dysfunction during weaning from mechanical ventilation

From these studies, ventilator-induced diaphragm dysfunction was defined in 2004 as loss of diaphragmatic force-generating capacity specifically ...

Fatal PCA Opioid-Induced Respiratory Depression

... Opioid-Induced Ventilatory Impairment ... Avoiding Adverse Events Secondary to Opioid-Induced Respiratory Depression: Implications for Nurse Executives and ...

Opioids and renal function - The Journal of Pain

... clinical implications of using opioids in patients with renal impairment. ... In dialysis patients meperidine induced definite impairment in the ventilatory ...

Opioid-induced Constipation: Old and New Concepts in Diagnosis ...

Emerging therapies for patients with symptoms of opioid-induced bowel dysfunction ... Opioid-induced constipation: pathophysiology, clinical consequences, and ...

Patient-Ventilator Interaction During Acute Lung Injury, and the Role ...

... respiratory failure and indirectly may impact clinical ... Cellular mechanisms implication in ventilator-induced diaphragmatic dysfunction.

Heart–Lungs interactions: the basics and clinical implications

... terms of clinical and/or oxygenation improvement [30, 37,38,39,40]. Cardiac dysfunction induced by weaning from mechanical ventilation.

163 Keeping Patients From Opioid-Induced Respiratory Depression

... patient safety considerations related to opioid-induced respiratory depression. We are doing a literature review and discussing a proposed ...