Current management of uveal melanoma

Intraocular Melanoma Treatment - Lurie Cancer Center

Plaque radiotherapy is a type of radiation therapy used to treat eye cancer. Radioactive seeds are attached to one side of a thin piece of metal ...

Survival Implications of Enucleation After Definitive Radiotherapy for ...

THE PROGNOSTIC influence of enucleation in the treatment of choroidal melanoma has long been debated. ... Zimmerman et al proposed that enucleation could be a ...

Ocular Melanoma - Symptoms, Causes, Treatment | NORD

Uveal melanomas can spread through the bloodstream, most often reaching the liver, where the cancer can become life-threatening. Conjunctival ...

Intraocular (Uveal) Melanoma Treatment (PDQ®) - Kaiser Permanente

This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it ...

Treatment of Uveal Melanoma With Radioactive Iodine 125 Implant ...

Objective: To review the current state of radiation therapy for uveal melanoma and compare particle radiation and brachytherapy.

Radiation therapy for uveal melanoma: a review of treatment

We believe that gamma knife therapy is clearly an option for the treatment of uveal melanomas. Its current best use is in patients with large tumors looking to ...

Practice Considerations for Proton Beam Radiation Therapy of ...

Uveal melanoma (UM) threatens patients with loss of vision, a painful eye needing enucleation (ie, amputation), and metastatic disease. Metastases develop in ...

Clinical Trials in Metastatic Uveal Melanoma: Current Status

The current landscape of systemic therapy for cutaneous melanoma is largely driven by immunotherapy. Although effective in treating patients ...

Diagnosis and Management of Choroidal Melanoma

When CM extends to periocular structures, exenteration may be agreed on as a means to prevent metastatic spread. If metastasis has already ...

AstraZeneca provides update on selumetinib in uveal melanoma

AstraZeneca today announced that the Phase III SUMIT study of selumetinib in combination with dacarbazine for the treatment of patients with metastatic uveal ...

Uveal Melanoma: Current Treatment Approaches - OncLive

The current treatment landscape in uveal has to do with 2 major approaches: one being local-regional approaches, liver-directed approaches.

Darovasertib, a novel treatment for metastatic uveal melanoma

Current Phase I/II clinical trials indicated that darovasertib, combined with the Mitogen-activated protein kinase/Extracellular (MEK) ...

Recent advancements in the management of... - F1000Research

Intravitreal injections of chemotherapy have also demonstrated excellent efficacy for vitreous seeds. Uveal melanoma, on the other hand, is ...

Current Treatment of Choroidal Melanoma - Medscape

Current treatment options of choroidal melanoma include enucleation, plaque brachytherapy, proton beam radiotherapy, stereotactic photon beam irradiation, local ...

LCD - MolDX: DecisionDx-UM (Uveal Melanoma) (L37070) - CMS

These patients benefit from early detection of metastatic disease when it can be most effectively treated. Patients with low metastatic risk can be removed from ...

Metastatic uveal melanoma showing durable response to anti-CTLA ...

Metastatic uveal melanoma (MUM) does not harbor typically targetable mutations, e.g., BRAF as in cutaneous melanoma. As a result, there is no proven therapy for ...

Ocular oncology: advances in retinoblastoma, uveal melanoma and ...

Currently EBRT is used to salvage eyes failing other treatments,4 but is regarded by many authorities as tantamount to treatment failure. Systemic chemotherapy ...

Proton Beam Irradiation of Uveal Melanomas - IOVS - ARVO Journals

The earliest treatment for uveal melanoma was removal of the eye. Today, enucleation has been supplanted by radiotherapy as the standard of care.

Practice Considerations for Proton Beam Radiation Therapy of ...

Radiation Therapy of Uveal Melanoma During the. Coronavirus Disease ... Currently, high-priority patients with cancer are being.

Metastatic uveal melanoma-A review of current therapies and future ...

This review will discuss the options for metastatic uveal melanoma including hepatic-directed therapies, systemic therapies, and future directions.