Impact of CRISPR in cancer drug discovery

While these results are promising, there is still much research to be done to maximize the technology's potential in cancer treatment. Blood ...

CRISPR 101: Drug discovery and CRISPR - Addgene Blog

High-throughput CRISPR screens can be used to inhibit, activate, or knockout many genes at a time to identify 'hits' - genes that affect disease ...

Missed Targets and Off-Target Effects - BioTechniques

The first step in drug development is to find a good target. Proteins that are essential for cancer cell growth are potential targets. Essential ...

Stanford explainer: CRISPR, gene editing, and beyond

Genetic diseases make up a big part of this category. Traditional medicines – small molecule drugs, surgery, and other methods – don't work for ...

Justice in CRISPR/Cas9 Research and Clinical Applications

The initial focus has been on cancer immunotherapy and correction of single gene disorders. ... For example, several teams have used the CRISPR/Cas9 system to ...

Gene editing in organoids: accounting for complexity in drug discovery

CRISPR allows researchers to target and edit specific genes in order to better understand the genome, human diseases and the effects of specific ...

Sunil Sharma and Rafaella Soldi Discuss the Impact of CRISPR in ...

... cancer research. Episode 41. Sunil Sharma and Raffaella Soldi Talk CRISPR For Unbiased Drug Screening for Rare Pediatric Cancers. Dr. Sunil ...

Drug screens and CRISPR combine to help make better cancer drugs

A new study has created the most comprehensive analysis for understanding how cancer drugs work at a molecular level.

What are genome editing and CRISPR-Cas9?: MedlinePlus Genetics

If the viruses attack again, the bacteria produce RNA segments from the CRISPR arrays that recognize and attach to specific regions of the ...

Exploring the Advantages and Limitations of CRISPR-Cas in Breast ...

CRISPR-Cas technology has developed rapidly and is now an efficient alternative for cancer treatment. CRISPR is naturally occurring genome ...

Is CRISPR Worth the Risk? - Yale Insights

A series of studies have suggested that CRISPR may cause cells to lose their cancer-fighting ability, and that it may do more damage to genes ...

Viewing Breast Cancer with a CRISPR Lens: The Potential of Gene ...

In short, the technology can be delivered into cells to modify genomic DNA of choice, which holds amazing potential in the treatment of genetic ...

Applications and challenges of CRISPR-Cas gene-editing to ...

Furthermore, the CRISPR-Cas system has been developed to fulfill its potential as a feasible treatment option for some infectious diseases, autoimmune disorders ...

The Functional Genomics Centre: building a single-cell CRISPR ...

What impact will single-cell CRISPR screens have on drug discovery? ... Pooled CRISPR screens require extensive data analysis, secondary screens, ...

Who We Are | CRISPR Therapeutics

Creating an impact ... The first-ever CRISPR-based therapy is a direct reflection of our patient-forward philosophy. This CRISPR/Cas9 therapy is now approved in ...

CRISPR Technology Explored in Oncology - YouTube

... cancer treatment. Read the full article HERE: https://www.targetedonc.com/view/the-promise-of-gene-editing-in-cancer-approaches-fruition For ...

Drug Discovery in the Age of Big Data - The Impact of RNAi ...

Now, by successfully harnessing CRISPR/Cas9 technology for genome editing, we can induce targeted, disease-specific mutations in the same RNAi ...

Using CRISPR, biologists find a way to comprehensively identify anti ...

In leukemia cells, the CRISPR-based method surveyed about 200 potential drug targets in proteins and successfully identified the 6 already known ...

CRISPR Tools Identify Gene Mutations That Drive Cancer

ETH Zurich researchers used combined CRISPR techniques to reveal unknown cancer-related mutations in the EGFR gene, identifying variants ...

Using CRISPR to decipher whether gene variants lead to cancer

Important for oncology ... Cell pools with different gene variants are crucial for research. That's because oncologists are increasingly analyzing ...