mRNA|based vaccines and therapeutics

From A to Z: An Alternative base modification for mRNA therapeutics

Messenger RNA (mRNA) technology has become popular in the last few years due to its use in COVID-19 vaccines. ... Compared to unmodified mRNAs, ...

expert reaction to study on understanding and preventing ...

A study published in Nature looks at unintended immune responses in mRNA therapeutics. ... “When you make mRNA vaccines, as mRNA is very unstable ...

mRNA vaccines: the post-pandemic outlook after a breakthrough year

mRNA-based vaccine hit the headlines in 2020 after the quick development of two candidates to protect against SARS-CoV-2.

mRNA Is Capable of Providing Solutions Far Beyond Vaccines

However, vaccines are not the only focus of mRNA therapeutics. It is also being developed for protein replacement therapy, gene editing, and ...

From Foundational Discoveries to Pandemic Proliferation of Impact

We knew that one of the advantages of an mRNA vaccine was how quickly it could be created,” Weissman said. In the COVID-19 mRNA vaccines, modified mRNA ...

Current Developments and Challenges of mRNA Vaccines

mRNA vaccines have brought about a great revolution in the vaccine fields owing to their simplicity and adaptability in antigen design, potential to induce ...

Analysis of mRNA Therapeutics and Vaccines

Enzymatic cleavage is required for this analysis because mRNA is such a large molecule. The established method required two challenging sample ...

Molecular Therapy Podcast: mRNA Vaccines with Dr. Norbert Pardi

Welcome to the first episode of the Molecular Therapy Podcast! Join Dr. Roland Herzog, Editor-in-Chief of Molecular Therapy and Professor of ...

Delivery of mRNA therapeutics - European Pharmaceutical Review

The success of mRNA vaccines against SARS-CoV-2 has quickly catapulted mRNA therapeutics as a disruptive, expanding drug category. Advances in ...

Combined Therapeutics mRNA-Based Vaccine Platform - Vial

The MOPCTx platform allows for the inhibition of protein expression in specific vulnerable tissues, enabling targeted vaccine treatment and preventing off- ...

mRNA vaccines may make unintended proteins, but there's no ...

mRNA therapeutics aim to coax a person's own cells to produce a protein that can treat a disease. But because foreign RNA usually means a virus ...

An overview of rational design of mRNA-based therapeutics and ...

Messenger RNA (mRNA)-based therapeutics and vaccines have emerged as a disruptive new drug class for various applications, including regenerative medicine ...

Development of mRNA vaccines and their prophylactic and ...

This review highlights the role of mRNA vaccines as prophylactic vaccines for prevention of future infections and as therapeutic vaccines for cancer ...

What are mRNA vaccines and how do they work?

These uses of mRNA vaccines are known as therapeutics as they prevent recurrence in people with an existing condition. What opportunities do ...

Advances in lipid nanoparticle mRNA therapeutics beyond COVID ...

The remarkable success of two lipid nanoparticle-mRNA vaccines against coronavirus disease (COVID-19) has placed the therapeutic and prophylactic potential ...

New COVID-19 sa-mRNA Results from CSL and Arcturus ...

mRNA vaccines help protect against infectious diseases by providing a blueprint for cells in the body to make a protein to help our immune ...

Process development challenges for mRNA vaccines and beyond

Although many people did not know about mRNA until the COVID-19 pandemic, researchers have studied the capabilities of RNA-based vaccines and therapeutics for ...

The Rise of mRNA Vaccines and Therapeutics

“Before COVID, we really didn't think mRNA vaccines would be a thing,” stated Jason Murphy, Ph.D., of Moderna at the University of Houston Drug ...

mRNA Therapeutics Market Size To Hit USD 39.99 Bn By 2033

Additionally, RNA vaccinations have a portion of advantages over Gene delivery in regards to production, dissemination, and efficacy. The need for mRNA ...

Analytical Solutions for mRNA Vaccines and Therapeutics

Messenger RNA (mRNA) therapy enables the body to make the proteins needed to prevent, treat or cure diseases but, unlike traditional ...