- A Protein|Truncating HSD17B13 Variant and Protection from ...🔍
- [PDF] A Protein‐Truncating HSD17B13 Variant and Protection from ...🔍
- A Protein|Truncating HSD17B13 Variant and Protection ...🔍
- HSD17B13 truncated variant is associated with a mild hepatic ...🔍
- A Protein|Truncating HSD17B13 Variant and Protection From ...🔍
- A protein|truncating HSD17B13 variant and protection from chronic ...🔍
- Sa1560 PROTEIN TRUNCATING SPLICE VARIANT 🔍
- A closer look at the mysterious HSD17B13🔍
[PDF] A Protein‐Truncating HSD17B13 Variant and Protection from ...
A Protein-Truncating HSD17B13 Variant and Protection from ...
A loss-of-function variant in HSD17B13 is associated with a reduced risk of chronic liver disease and of progression from steatosis to steatohepatitis.
[PDF] A Protein‐Truncating HSD17B13 Variant and Protection from ...
A loss‐of‐function variant in HSD17B13 was associated with a reduced risk of chronic liver disease and of progression from steatosis to steatohepatitis.
A Protein-Truncating HSD17B13 Variant and Protection from ...
A splice variant (rs72613567:TA) in HSD17B13, encoding the hepatic lipid droplet protein hydroxysteroid 17-beta dehydrogenase 13, was found to ...
A Protein-Truncating HSD17B13 Variant and Protection ... - PubMed
Results: A splice variant (rs72613567:TA) in HSD17B13, encoding the hepatic lipid droplet protein hydroxysteroid 17-beta dehydrogenase 13, was ...
A Protein-Truncating HSD17B13 Variant and Protection from ...
A genetic variant conferring a loss of function on the enzyme hydroxysteroid 17-beta dehydrogenase 13, expressed in the membrane surrounding the hepatic ...
A Protein-Truncating HSD17B13 Variant and Protection from ...
Results A splice variant (rs72613567:TA) in HSD17B13, encoding the hepatic lipid droplet protein hydroxysteroid 17-beta dehydrogenase 13, was associated with ...
A Protein-Truncating HSD17B13 Variant and Protection ... - Ex Libris
A genetic variant conferring a loss of function on the enzyme hydroxysteroid 17-beta dehydrogenase 13, expressed in the membrane surrounding the hepatic ...
A Protein-Truncating HSD17B13 Variant and Protection from ...
A genetic variant conferring a loss of function on the enzyme hydroxysteroid 17-beta dehydrogenase 13, expressed in the membrane surrounding the hepatic ...
HSD17B13 truncated variant is associated with a mild hepatic ...
A protein-truncating HSD17B13 variant (rs72613567) was shown to protect individuals from alcoholic and non-alcoholic liver disease.
A Protein-Truncating HSD17B13 Variant and Protection From ...
abulhusn2018.pdf - Free download as PDF File (.pdf), Text File (.txt) or read online for free.
A protein-truncating HSD17B13 variant and protection from chronic ...
I148M allele and resulted in an unstable and truncated protein with reduced enzymatic activity. CONCLUSIONS A loss-of-function variant in ...
Sa1560 PROTEIN TRUNCATING SPLICE VARIANT (RS72613567 ...
Request PDF | Sa1560 PROTEIN TRUNCATING SPLICE VARIANT (RS72613567) IN HSD17B13 GENE DOES NOT CONFER PROTECTION TO NAFLD IN INDIAN POPULATION | Background: ...
A closer look at the mysterious HSD17B13 - PMC
The human HSD17B13 gene encodes a 300-amino-acid protein that is localized on lipid droplet (4). Interestingly, a few single-nucleotide polymorphisms ( ...
An HSD17B13 variant reduces cirrhosis risk - Nature
The HSD17B13 variant was found to alter mRNA splicing, yielding a truncated protein with reduced enzymatic activity against the experimentally ...
A closer look at the mysterious HSD17B131
mouse Hsd17b13 gene knockout does not seem to protect the liver from ... A protein-truncating HSD17B13 variant and protection from chronic liver ...
HSD17B13: A Potential Therapeutic Target for NAFLD - Frontiers
A Protein-Truncating HSD17B13 Variant and Protection from Chronic. Liver Disease. N. Engl. J. Med. 378 (12), 1096–1106. doi:10.1056 ...
impact of a loss-of-function variant in hsd17b13 on hepatic ...
A Protein-. Truncating HSD17B13 Variant and Protection from Chronic Liver Disease. N Engl J. Med. 2018 Mar 22;378(12):1096-1106. doi: 10.1056/NEJMoa1712191 ...
Therapeutic opportunities for the treatment of NASH with genetically ...
aminase levels, with this variant being shown to protect ... A protein-truncating HSD17B13 variant and protection from chronic liver · disease.
Splice variant rs72613567 prevents worst histologic outcomes in ...
Hydroxysteroid 17-#x03B2; dehydrogenase 13 (HSD17B13) is a lipid droplet-associated protein; its gene-encoding variants affect the chronic liver diseases, ...
[PDF] Loss-of-function HSD17B13 variants, non-alcoholic ...
A Protein‐Truncating HSD17B13 Variant and Protection from Chronic Liver Disease · N. Abul-HusnXi-ping Cheng +45 authors. F. Dewey. Medicine. The New England ...