[PDF] Efficacy and safety of incretin therapy in type 2 diabetes

Efficacy and Safety of Incretin Therapy in Type 2 Diabetes

FEWER THAN HALF OF US ADULTS with type 2 diabetes reach a he- moglobin A1c (HbA1c) level of less than 7% despite several available therapies.1 Ineffective ...

Efficacy and Safety of Incretin Therapy in Type 2 Diabetes

Incretins lowered hemoglobin A1c compared with placebo (weighted mean difference, −0.97% [95% confidence interval {CI}, −1.13% to −0.81%] for GLP-1 analogues ...

Efficacy and safety of incretin therapy in type 2 diabetes - PubMed

Incretin therapy offers an alternative option to currently available hypoglycemic agents for nonpregnant adults with type 2 diabetes, ...

Efficacy and safety of incretin therapy in type 2 diabetes - NCBI

This review of two new drug classes (glucagon-like peptide 1 analogues and dipeptidyl peptidase 4 inhibitors) concluded that incretin-based therapies offer ...

[PDF] Efficacy and safety of incretin therapy in type 2 diabetes

Careful postmarketing surveillance for adverse effects, especially among the DPP4 inhibitors, and continued evaluation in longer-term studies and in ...

Efficacy and Safety of Incretin-Based Therapies in Patients with Type ...

3 Exenatide is available in the United States; it is indicated for adjunctive therapy to improve glycemic con- trol in patients with type 2 diabetes that is ...

Safety and Efficacy of Incretin-Based Therapies in Patients With ...

INDEX WORDS: Type 2 diabetes mellitus (T2DM); chronic kidney disease (CKD); systematic review; epidemiology; meta-analysis; pharmacoepidemiology ...

Efficacy and Safety of Incretin Therapy in Type 2 Diabetes

... In recent times incretin-based drugs have emerged as notable effective therapeutic agents for the management of Type 2 diabetes mellitus (T2DM) and obesity ...

Efficacy and Safety of Incretin-Based Therapies in Patients with Type ...

Incretin-based therapies enhance endogenous insulin secretion without causing hypoglycemia or weight gain. This review focuses on the efficacy ...

Efficacy and Safety of Incretin-Based Therapies in Patients with Type ...

Impairment of incretin activity plays an integral part in the metabolic derangement underlying type 2 diabetes. Glucagon-like peptide–1 (GLP-1) receptor ...

Efficacy and safety of incretin-based therapies: Clinical trial data

Conclusion. In addition to decreasing glycemia in type 2 diabetes, incretin therapies may improve other important parameters, including beta-cell function, ...

Efficacy and safety of incretin therapy in type 2 diabetes

This article refers to a new therapeutic tool for the treatment of type II diabetes: the incretin system. The efficacy and safety of incretin therapy for ...

Safety and Efficacy of Incretin-Based Therapies in Patients With ...

Compared to placebo, incretin-based therapies significantly reduced HbA1c levels (n = 9; weighted mean difference, −0.64; 95% CI, −0.79 to −0.48; I2 = 43%); ...

Efficacy and Safety of Incretin-Based Therapies in Patients with Type ...

Additionally, we examine the utility of GLP-1 receptor agonists and DPP-4 inhibitors as these agents may be applied at different stages of type 2 diabetes ...

All of the incretin-related therapies appear to be well suited for use in elderly populations, with no additional safety considerations directly ...

Incretin-Based Therapies in Type 2 Diabetes Mellitus

Two new drugs, exenatide (GLP-1 mimetic) and sitagliptin [dipeptidyl peptidase (DPP) 4 inhibitor], have been approved by regulatory agencies for treating T2DM.

Comparison of efficacy between incretin-based therapies for type 2 ...

Incretin based therapies are available as either incretin mimetics (also called GLP-1 agonists) or incretin enhancers (DPP-4 inhibitors).

original article - Efficacy and safety of canagliflozin when used in ...

Efficacy and safety of canagliflozin when used in conjunction with incretin-mimetic therapy in patients with type 2 diabetes. G. Fulcher1, D. R. Matthews2, V ...

Efficacy and Safety of GLP-1 Medicines for Type 2 Diabetes and ...

The hemoglobin A1c (HbA1c) reduction and weight loss were greater with semaglutide relative to therapy with dulaglutide (6). Superior reduction ...

Efficacy and Safety of Incretin Therapy in Type 2 Diabetes - Scribd

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