[PDF] LRPPRC and SLIRP synergize to maintain sufficient and ...

LRPPRC and SLIRP synergize to maintain sufficient and orderly ...

C5024T of the tRNAAla gene) into Slirp knockout mice causes an additive effect on mitochondrial translation leading to embryonic lethality and ...

LRPPRC and SLIRP synergize to maintain sufficient and orderly ...

Abstract. In mammals, the leucine-rich pentatricopeptide repeat protein (LRPPRC) and the stem-loop interacting RNA-binding protein (SLIRP) form a complex i.

[PDF] LRPPRC and SLIRP synergize to maintain sufficient and ...

It is reported that the LRPPRC/SLIRP protein complex is critical for maintaining normal complex I levels and that it also coordinates mitochondrial ...

LRPPRC and SLIRP synergize to maintain sufficient and orderly ...

Although pathogenic mutations in the LRPPRC and SLIRP genes cause devastating human mitochondrial diseases, the in vivo function of the ...

LRPPRC and SLIRP synergize to maintain sufficient and ... - PubMed

LRPPRC and SLIRP synergize to maintain sufficient and orderly mammalian mitochondrial translation. Nucleic Acids Res. 2024 Oct 14;52(18):11266-11282. doi ...

[PDF] LRPPRC and SLIRP synergize to maintain sufficient and ...

LRPPRC and SLIRP synergize to maintain sufficient and orderly mammalian mitochondrial translation. Diana Rubalcava-Gracia, Kristina Bubb, Fredrik Levander ...

LRPPRC is a mitochondrial matrix protein that is conserved in ...

Request PDF | LRPPRC is a mitochondrial matrix ... LRPPRC and SLIRP synergize to maintain sufficient and orderly mammalian mitochondrial translation.

[PDF] LRPPRC/SLIRP suppresses PNPase-mediated mRNA decay ...

2013. 207 Citations · PDF. Add to Library. Alert. 1 Excerpt. LRPPRC and SLIRP synergize to maintain sufficient and orderly mammalian mitochondrial translation.

https://api.repository.cam.ac.uk/server/api/core/bitstreams/6db04c7a ...

To summarize, we report that LRPPRC and SLIRP synergize to maintain orderly mtDNA gene expression that affect levels of complex I and mouse embryonic ...

(PDF) SLIRP stabilizes LRPPRC via an RRM–PPR protein interface

... LRPPRC and SLIRP synergize to maintain sufficient and orderly mammalian mitochondrial translation. Article. Aug 2024; NUCLEIC ACIDS RES.

The mitochondrial mRNA-stabilizing protein SLIRP regulates ...

Download PDF. Article; Open access ... LRPPRC and SLIRP synergize to maintain sufficient and orderly mammalian mitochondrial translation.

LRPPRC and SLIRP Interact in a Ribonucleoprotein Complex That ...

The resultant defect in mitochondrial protein synthesis in LSFC cells disproportionately affects the COX subunits, leading to an isolated COX ...

LRPPRC and SLIRP Interact in a Ribonucleoprotein Complex That ...

View PDF. Tools. Add to favorites ... LRPPRC and SLIRP synergize to maintain sufficient and orderly mammalian mitochondrial translation.

Activation mechanism of mitochondrial translation by LRPPRC-SLIRP

... SLIRP (SRA stem-loop-interacting RNA-binding protein) that. 41 plays roles in LRPPRC stability and maintaining steady-state mRNA levels13. SLIRP silencing. 42.

LRPPRC/SLIRP suppresses PNPase-mediated mRNA decay and ...

The LRPPRC/SLIRP complex is required to maintain poly(A) tails of mitochondrial mRNAs ... sufficient for polyadenylation and that MTPAP requires LRPPRC for ...

CRISPR Functional Genomics - SciLifeLab

LRPPRC and SLIRP synergize to maintain sufficient and orderly mammalian mitochondrial translation. ... PDF. Full text. Compared to the ...

Leigh Syndrome-inducing Mutations Affect LRPPRC / SLIRP ...

We observed that the LRPPRC/SLIRP complex formation is maintained in the cases of LRPPRC single deletions delV866 and delK909, although slightly ...

High mitochondrial DNA levels accelerate lung adenocarcinoma ...

Larsson, LRPPRC and SLIRP synergize to maintain sufficient and orderly mammalian mitochondrial translation. ... Download this article as a PDF ...

mTORC1 is required for expression of LRPPRC and cytochrome-c ...

This strengthens the hypothesis that LSFC fibroblasts depend on extramitochondrial metabolism to maintain ATP levels. Although patient ...

MTH1 protects platelet mitochondria from oxidative damage and ...

In addition, Slirp has been reported to modulate mitochondrial protein synthesis and prevents LRPPRC degradation. The significantly reduced ...