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[PDF] TNF|α blockade induces IL|10 expression in human CD4 T ...


TNF-α blockade induces IL-10 expression in human CD4+ T cells

IL-17+ CD4+ T (Th17) cells contribute to the pathogenesis of several human inflammatory diseases. Here we demonstrate that TNF inhibitor ...

TNF-α blockade induces IL-10 expression in human CD4+ T cells

IL-17+ CD4+ T (Th17) cells contribute to the pathogenesis of several human inflammatory diseases. Here we demonstrate that TNF inhibitor (TNFi) drugs induce ...

[PDF] TNF-α blockade induces IL-10 expression in human CD4+ T ...

It is shown that inhibitors of the pro-inflammatory cytokine TNF, used in patients undergoing anti- inflammatory treatment, might mediate the acquisition of ...

(PDF) TNF-α blockade induces IL-10 expression in human CD4+ T ...

PDF | IL-17+ CD4+ T (Th17) cells contribute to the pathogenesis of several human inflammatory diseases. Here we demonstrate that TNF inhibitor (TNFi).

TNF Blockade Maintains an IL-10+ Phenotype in Human Effector ...

Publisher's PDF, also known as Version of record. Link to ... TNF-α blockade induces IL-10 expression in human CD4+ T cells. Nat.

TNF-α blockade induces IL-10 expression in human CD4+ T cells

TNF-α blockade induces IL-10 expression in human CD4+ T cells. Hayley G. Evans, Urmas Roostalu, Gina J. Walter, Nicola J. Gullick, Klaus S. Frederiksen, Ceri ...

Identification of a transcription factor network regulating anti-TNF ...

TNF-α blockade induces IL-10 expression in human CD4+ T cells . Nat Commun. 2014. ,. 5. ,. 3199 . doi:10.1038/ncomms4199 · Google Scholar.

Anti‐TNF treatment negatively regulates human CD4+ T‐cell ...

et al., TNF‐α blockade induces IL‐10 expression in human CD4+ T cells. Nat ... Click here for additional data file. (7.7MB, pdf). Articles from European ...

Identification of a transcription factor network regulating anti-TNF ...

Request PDF | Identification of a transcription factor network regulating anti-TNF ... TNF-α blockade induces IL-10 expression in human CD4+ T ...

Identification of a transcription factor network regulating anti-TNF ...

anti-TNF mediated IL10 expression in human CD4+ T cells. Giovanni ... TNF-α blockade induces IL-10 expression in human CD4+ T cells. Nat ...

IL-10 production by CD4+ effector T cells: a mechanism for self ...

This observation suggested that IL-10 expression may be induced in Th1 cells in response to host infection rather than representing the emergence of a specific ...

The dichotomous outcomes of TNFα signaling in CD4+ T cells

Immunoregulatory activity of recombinant human tumor necrosis factor (TNF)-alpha: induction of TNF receptors on human T cells and TNF-alpha-mediated enhancement ...

TNF-α blockade induces IL-10 expression in human CD4+ T cells

Frederic Geissmann; Bruce W. Kirkham; Leonie S. Taams. Список літератури. Miossec, P., Korn, T. & Kuchroo, V. K. Interleukin-17 and type 17 ...

Critical Role for TNF in the Induction of Human Antigen-Specific ...

Intriguingly, TNFRII is also highly expressed on CD4+CD25hi regulatory T cells (Tregs) (14, 15). Tregs are important for the maintenance of peripheral tolerance ...

Molecular and functional heterogeneity of IL-10-producing CD4 + T ...

The combinatorial expression of co-inhibitory receptors is sufficient to discriminate IL-10-producing CD4+ T cells with regulatory function from ...

IL-10 signaling in CD4+ T cells is critical for the pathogenesis of ...

Blocking IL-10 signaling in T cells rendered mice, especially female mice, highly susceptible to collagen-induced arthritis. T-cell activation ...

The multifaceted nature of IL-10: regulation, role in immunological ...

Induction of a homogeneous population of IL-10-producing CD4 T cells by a ... Il-10 exacerbates xenogeneic gvhd by inducing massive human T cell expansion.

IL-10 Family Cytokines IL-10 and IL-22 - Cell Press

Interestingly, anti-TNF-a therapy reduces the IL-22BP expression in CD4+ T cells from IBD patients ... receptor induces human type 1 regulatory T ...

IL-10: The Master Regulator of Immunity to Infection - AAI Journals

Nevertheless, IL-10 can act directly on CD4+ T cells, inhibiting proliferation and production of IL-2, IFN-γ, IL-4, IL-5 and TNF-α (5, 8, 9).

Biology and therapeutic potential of interleukin-10

M.G.. Roncarolo . 1996 . Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells . J. Exp. Med. 184. : 19. –. 29 . https://doi ...