“Mirror|image” molecules pave new path for cancer drug discovery

“Mirror-image” molecules pave new path for cancer drug discovery

Scripps Research scientists have developed a new strategy for identifying small molecules that can change the function of proteins, offering a promising path ...

Seeing double: Designing drugs that target 'twin' cancer proteins

More research is needed to discover whether the new compounds ... 'Mirror-image' molecules pave new path for cancer drug discovery. Apr ...

New Way To Potentially Slow Cancer Growth - Drug Discovery Online

Revealing key protein targets that, when disrupted with certain chemical compounds (or small molecules), halt cancer cell growth may eventually ...

Breakthrough in mirror molecule synthesis opens doors for drug ...

A University of Texas at Dallas chemist and his colleagues have developed a new chemical reaction that will allow researchers to synthesize ...

Wafik S. El-Deiry, MD, PhD, FACP on LinkedIn: 'Mirror-image ...

'Mirror-image' molecules pave new path for cancer drug discovery https://lnkd.in/eVWbThmW.

Precise genome engineering and protein activity profiling uncover ...

"This approach integrates two innovative methods, that together, form a target and drug discovery strategy for nominating new cancer treatments, ...

Cancer | Scripps Research

“Mirror-image” molecules pave new path for cancer drug discovery ... By comparing how mirror image versions of small molecules impact clusters of proteins, ...

Advancing Cancer Drug Discovery Through Collaboration And ...

“By essentially gluing those two proteins together, you get a new biological effect that results from the unnatural union of protein A and B.

drug discovery - Scientific Inquirer

“Mirror-image” molecules pave new path for cancer drug discovery. May 2, 2023. “Mirror-image” molecules pave new path for cancer drug discovery.

Drug Discovery by Molecular Imaging and Monitoring Therapy ...

Here, we review molecular imaging applications in drug development, with an emphasis on oncology. Monitoring and assessing the efficacy of anti-cancer therapies ...

'Mirror-image' protein factories could one day make durable drugs ...

Other researchers have shown that mirror-image versions of short strands of DNA and RNA called aptamers can serve as potent drug candidates that ...

Rethinking and rigor brings promising protein for cancer therapy

... new drug molecules. Nov 21, 2022. 'Mirror-image' molecules pave new path for cancer drug discovery. Apr 27, 2023. Enzymatic danse macabre of ...

Cancer Drug Discovery: A Molecular Journey to Targeted Treatment

Cancer drug discovery has made great advances since its earliest steps. Cytotoxic drugs affect healthy cells, as well as the tumor, ...

New mirror-image molecules could lead to better medicines

Scientists have developed a new technology for designing mirror-image versions of molecules, paving the way for longer lasting medicines.

Recent advances in targeting the “undruggable” proteins: from drug ...

Owing to the rapid development of molecular biology, tremendous progress has been made in the past decades to uncover key biomacromolecules ...

Pathway-Based Drug-Repurposing Schemes in Cancer: The Role of ...

As is known, biological functions are often represented as an interaction network of molecules within the cells. Such interactions are often ...

Applications and Showcases of RNA Sequencing Throughout the ...

Advancing drug discovery processes with NGS & RNA sequencing. Explore examples and showcases: how RNA-Seq aids small molecule drug discovery ...

Mirror-Image Chemistry Enables New Approach for Targeting an ...

This illustration shows molecular models of left-handed and right-handed KRas. The two molecules are mirror images of each other. Summary. MSK ...

Artificial Intelligence in Cancer Research and Precision Medicine

These applications range from detection and classification of cancer, to molecular characterization of tumors and their microenvironment, to ...

Navigating the Molecular Pathway: Small Molecule Drug Discovery ...

It begins with identifying initial “hits”—molecules with potential biological activity—and continues through a rigorous series of optimizations ...