1 Clinical and biological insights from viral genome sequencing 1 2 ...

Clinical and biological insights from viral genome sequencing - Nature

One of the main applications and reasons for sequencing viruses is the detection of drug resistance. For example, the management of highly ...

Clinical and biological insights from viral genome sequencing

Whole-genome sequencing (WGS) of pathogens is becoming increasingly important not only for basic research but also for clinical science and practice. In ...

1 Clinical and biological insights from viral genome sequencing 1 2 ...

Figure 1: Major methods for sequencing viral genomes from clinical specimens. 538. All specimens originally comprise a mix of host (in blue) and pathogen ...

(PDF) Clinical and biological insights from viral genome sequencing

Whole-genome sequencing (WGS) of pathogens is becoming increasingly important not only for basic research but also for clinical science and practice.

Clinical and biological insights from viral genome sequencing

Sequencing viral DNA and RNA is an important part of clinical practice, although, so far, mostly subgenomic fragments have been sequenced.

Clinical and biological insights from viral genome sequencing - Apollo

In virology, WGS is important for the development of novel treatments and vaccines, and for increasing the power of molecular epidemiology and evolutionary ...

Clinical and biological insights from viral genome sequencing - OUCI

A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control. eLife 2, e01123 (2013). https ...

Clinical and biological insights from viral genome sequencing

Whole-genome sequencing (WGS) of pathogens is becoming increasingly important not only for basic research but also for clinical science and practice.

Viral Genome Sequencing

It involves acquiring viral genome sequences, plus interpreting the encoded information and variant data through bioinformatics analytics. A frequently utilized ...

A collaborative approach to improve representation in viral genomic ...

... sequencing is the most widely adopted for SARS-CoV-2 genome sequencing. ... 1 and 2. We ... Clinical and biological insights from viral genome sequencing.

Viral genome sequencing methods: benefits and pitfalls of current ...

Whole genome sequencing of viruses provides high-resolution molecular insights, enhancing our understanding of viral genome function and ...

A complete protocol for whole-genome sequencing of virus from ...

Our protocol is able to generate the viral dominant genome sequence starting from clinical samples. It is based on a multiplex PCR amplicon sequencing coupled ...

Whole genome sequencing of Herpes Simplex Virus 1 directly from ...

2014a), notably because of difficulties in sequencing viruses from clinical material in a high-throughput manner. The viral genome size (152 kb) ...

Viral genomics in Ebola virus research | Nature Reviews Microbiology

Advances in the sequencing and functional characterization of both pathogen and host genomes have provided a wealth of knowledge to clinicians, ...

Rapid implementation of SARS-CoV-2 sequencing to investigate ...

We sequenced 1000 samples producing 747 high-quality genomes. We combined epidemiological and genomic analysis of the 299 patients from our hospital and ...

Genetic Surveillance of Five SARS-CoV-2 Clinical Samples in ...

The viral genomes were obtained with 96% coverage using nanopore sequencing. Forty-five missense nucleotide mutations were identified; out of ...

Complete viral RNA genome sequencing of ultra-low copy samples ...

The methods presented here are scalable to large numbers of samples and capable of generating full or near full length viral genomes from clone and clinical ...

From Clinical Specimen to Whole Genome Sequencing of A(H3N2 ...

(1) Background: Over the last few years, there has been growing interest in the whole genome sequencing (WGS) of rapidly mutating pathogens, ...

Optimisation and evaluation of viral genomic sequencing of SARS ...

Sequencing of SARS-CoV-2 from rapid diagnostic tests (RDTs) can bolster viral genomic surveillance efforts; however, approaches to maximise ...

1 Introduction | Genomic Epidemiology Data Infrastructure Needs for ...

When combined with epidemiological information, genomic sequencing can be particularly useful for investigating outbreaks of RNA viruses, such as SARS-CoV-2.