A Genome|Wide Scan for Urinary Albumin Excretion in Hypertensive ...

A genome-wide scan for urinary albumin excretion in hypertensive ...

Albuminuria increases the risk of cardiovascular events in patients with essential hypertension and diabetic subjects. The heritability (h2) of albuminuria ...

A Genome-Wide Scan for Urinary Albumin Excretion in Hypertensive ...

ACR and covariates were available in 1727 individuals (mean age, 57.1 years). Estimates of h2 were obtained by using variance component ...

A Genome-Wide Scan for Urinary Albumin Excretion in Hypertensive ...

The heritability (h2) of albuminuria in multiplex hypertensive families is unknown. We calculated the familial aggregation of urine albumin: ...

A genome-wide scan for urinary albumin excretion in hypertensive ...

Dive into the research topics of 'A genome-wide scan for urinary albumin excretion in hypertensive families'. Together they form a unique fingerprint. Sort ...

A genome-wide scan for urinary albumin excretion in hypertensive ...

The heritability (h2) of albuminuria in multiplex hypertensive families is unknown. We calculated the familial aggregation of urine albumin:creatinine ratio ( ...

Genome-wide association study of urinary albumin excretion rate in ...

In the discovery stage, five single nucleotide polymorphisms in the GLRA3 gene were strongly associated with albuminuria (p < 5 × 10(-8)). In ...

A genome-wide linkage scan for genes controlling variation in ...

The support for linkage of urinary albumin excretion to chromosome 21p with a peak at 13 cM is in contrast with the findings on chromosomes 5q, ...

Genome-wide linkage analysis to urinary microalbuminuria in a ...

In a genome-wide linkage analysis of families enriched for hypertension, urinary microalbumin was shown to be heritable (h2= 0.49), and suggestive linkage [ ...

Albuminuria in hypertension - Nature

The prevalence of albuminuria was determined using a positive dipstick test and was 13.4%. The prevalence rates of elevated Urine Albumin-to- ...

Genome-wide linkage analysis to urinary microalbuminuria in a ...

Suggestive evidence exists in Framingham Heart Study families for linkage to a novel locus on chromosome 8q to levels of urinary microalbumin excretion. This ...

Genetic bases of urinary albumin excretion and related traits ... - LWW

... hypertension. To unravel genetic variants of susceptibility, candidate gene, linkage and genome wide scan analysis has been used. In spite of the great ...

Genome-wide scans for microalbuminuria in Mexican Americans

Microalbuminuria, defined as urine albumin-to-creatinine ratio of 0.03 to 0.299 mg/mg, is a major risk factor for cardiovascular disease. Several genetic ...

Genetic Association of Albuminuria with Cardiometabolic Disease ...

Excretion of albumin in urine, or albuminuria, is associated with the development of multiple cardiovascular and metabolic diseases.

Urinary albumin excretion is associated with impaired flow - Nature

We hypothesized that increased urinary albumin excretion in hypertensive patients is associated with systemic vascular dysfunction, thereby ...

A genome-wide linkage scan for genes controlling variation ... - OUCI

A genome-wide linkage scan for genes controlling variation in urinary albumin excretion in type II diabetes · List of references · Publications that cite this ...

Genome scan of glomerular filtration rate and albuminuria

Abstract. Background. Albuminuria and reduced glomerular filtration rate (GFR) are markers of renal dysfunction associated with hypertension ...

Genome-wide linkage analysis to urinary microalbuminuria ... - CORE

... genome-wide scan for urinary albumin excretion in hypertensive families. Hypertension. 42:291–296, 2003. 15. DAWBER TR, MEADORS GF, MOORE FE: Epidemiologic ...

Value of routine urine examinations including microalbuminuria in ...

Many published studies have reported that urinary albumin excretion, as one of the earliest markers for hypertension-mediated organ damage ...

Microalbuminuria in Type 2 Diabetes and Hypertension

Urinary albuminuria comprises 20–70% or urinary total protein excretion. Measuring urinary albumin excretion by dipstick without simultaneously ...

Genome scan of glomerular filtration rate and albuminuria

To determine whether unique and/or common locus (or loci) regulate urinary albumin excretion and. GFR in the presence of hypertension, we ...