A Multi|Omics Analysis Revealing Novel CpG Sites and Their ...

A Multi-Omics Analysis Revealing Novel CpG Sites and Their ...

Our findings provide new insights into the epigenetic architecture of T2D, revealing novel genetic susceptibilities and highlighting potential ...

A Multi-Omics Analysis Revealing Novel CpG Sites and Their ...

Functional Analyses: Through whole-genome bisulfite sequencing (WGBS) and RNA-Seq analyses using data from PANC-DB, we identified 10 and 23 CpGs ...

Elucidating the Epigenetic Landscape of Type 2 Diabetes

Request PDF | Elucidating the Epigenetic Landscape of Type 2 Diabetes: A Multi-Omics Analysis Revealing Novel CpG Sites and Their ...

Elucidating the Epigenetic Landscape of Type 2 Diabetes - OUCI

Elucidating the Epigenetic Landscape of Type 2 Diabetes: A Multi-Omics Analysis Revealing Novel CpG Sites and Their Association with Cardiometabolic Traits.

A multi-omics approach to reveal critical mechanisms of activator ...

The sequencing output was analyzed using Bismark software to compile CpG sites ... analysis revealed that JunD expression level impacts its binding sites ...

Integrative multi-omic analysis identifies genetically influenced DNA ...

The imputation-based approach identified DNA methylation at cytosine-phosphate-guanine sites (CpGs) associated with BrCa and PrCa risk utilising ...

Multi-omics analysis identifies CpGs near G6PC2 mediating the ...

We also used a two-sample MR strategy to perform replication analysis for CpG sites ... reveals diverse mechanisms for novel genetic Loci ...

Epigenome-Wide Association Study Reveals CpG Sites ... - NCBI

We report novel associations between TSH, thyroid hormones, and blood-based DNA methylation. This study advances our understanding of thyroid ...

A Novel Multi-Omics Analysis Model for Diagnosis and Survival ...

Additionally, investigation of the potential CpG sites of risk gene cluster demonstrated 32 CpG ... Revealed by Bioinformatics Analysis of ...

Integrative omics analysis reveals epigenomic and transcriptomic ...

... CpG sites. The imaging transcriptional analysis is a versatile ... novel systems approach to brain structure: individualized structural covariance ...

Multi-Omics Analysis Reveals MicroRNAs Associated ... - Frontiers

Alterations in DNA methylation levels of CpG sites annotated to 38 of these miRNAs were associated with the same trait(s). Moreover, we found ...

An integrated -omics analysis of the epigenetic landscape of gene ...

... CpG islands overlap with promoter regions or transcription factor binding sites ... his CpG annotation and code for the gene ontology analysis.

Multi-Omics Integration Reveals Only Minor Long-Term Molecular ...

... CpG sites in the top 150 differentially methylated CpG sites. (D) ... EWAS analysis reveals that, though not genome-wide significant, there ...

A Novel Tool for Multi-Omics Network Integration and Visualization

... analyzed, mapping each one with the respective CpG sites. ... their inherent characteristic of having relations solely among their own CpG sites.

Multi-omic analysis of gametogenesis reveals a novel signature at ...

The presence of both marks was strongly associated with highest gene expression. Assessment of their co-localization with transcription regulators (SLY, SOX30) ...

Longitudinal analysis of epigenome-wide DNA methylation reveals ...

Overall, the identification of novel CpG sites associated with BMI change and their functional characterization provides a potential insight ...

A multi-omic analysis of birthweight in newborn cord blood reveals ...

After quality control and filtering, 417572 CpG sites for 460 samples were retained for subsequent analysis and methylation levels were expressed as beta values ...

meGPS: a multi-omics signature for hepatocellular carcinoma ...

This study proposes a procedure for multi-omics GPS identification and develops a novel ... CpG sites was smaller in HCC than in non-tumor ...

The dynamics of methylation of CpG sites associated with SLE ...

Objective—Cross-sectional studies have revealed associations between DNA methylation and systemic lupus erythematosus (SLE) outcomes. To study ...

Multi‐Omics Factor Analysis—a framework for unsupervised ...

Methylation data were transformed to M‐values, and we extracted the top 1% most variable CpG sites excluding sex chromosomes (D = 4,248). We included ...