- A Review on Significance of Identifying an Appropriate Solid Form ...🔍
- Solid form screening – A review🔍
- A guide to achieving the optimal solid form🔍
- Solid|form development🔍
- Review Physical stability of pharmaceutical formulations🔍
- Solid form screening and selection🔍
- Solid form changes during drug development🔍
- The Significance of Solid Form Science🔍
A Review on Significance of Identifying an Appropriate Solid Form ...
A Review on Significance of Identifying an Appropriate Solid Form ...
Identifying a thermodynamically stable and acceptable solid form is an essential part that follows drug discovery. In past, overall goal of ...
A Review on Significance of Identifying an Appropriate Solid Form ...
PDF | In recent years, solid form screening has become an integral and mandatory part of drug development. Solid form screening typically involves.
Solid form screening – A review - ScienceDirect.com
Solid form screening, the activity of generating and analysing different solid forms of an active pharmaceutical ingredient (API), has become an essential ...
A guide to achieving the optimal solid form - Sterling Pharma Solutions
Because an API's physical properties, as well as the crystal lattice packing arrangement, have a significant impact on therapeutic performance, ...
Solid-form development: the key to API success?
Moreover, understanding the physical properties of the solid form of the API can help lead to improvements in manufacturing processes, such as faster ...
Review Physical stability of pharmaceutical formulations: solid-state ...
Physical stability, along with chemical stability and microbiological stability, has been of industrial and regulatory interest for a long time [1], [2]. Proper ...
Solid form screening and selection: Why chemistry-led design brings ...
This is for two main reasons; firstly the FDA mandates such a study before clinical use, and secondly, appropriate solid form selection allows ...
Solid form changes during drug development: good, bad, and ugly ...
The relevance of solid form in drug development ... This example has clearly displayed the utility of identifying the appropriate salt form ...
The Significance of Solid Form Science - The Medicine Maker
Once a pharmaceutical company has identified a molecule they want to move through to the clinic, understanding and choosing the right solid form ...
Solid Form Screenings in Pharmaceutical Development - PubMed
Solid form screening is a crucial step in new drug development because solid forms of a drug substance significantly affect stability, ...
Solid Form and Drug Development | Request PDF - ResearchGate
Request PDF | Approaches to Solid-Form Screening: Solid Form and Drug Development | The first step in identifying the optimal solid form for development is ...
Q&A: Getting solid form selection right in early drug development
Different solid forms can vary in their tendency for chemical and physical stability both during the manufacture and storage of the drug product ...
The Importance of Solid-State Analysis in Dissolution
In a recent review,. Pudipeddi and Serajuddin (3) gathered the ... peaks of the solid forms identified in the Raman spectra. In the ...
The importance of solid form science in modern drug development
These methods are typically based on screening and manipulating the solid form of a drug candidate. Identifying an ideal solid form of an ...
Pharmaceutical Properties – The Importance of Solid Form Selection
The selection of the solid form for development is a milestone in the conversion of a new chemical entity into a drug product.
X-ray Powder Diffraction in Solid Form Screening and Selection
A variety of screens can be performed including polymorph, salt, co-crystal, amorphous, and amorphous dispersion. X-ray powder diffraction (XRPD) ...
a perspective on the interrelationships between different solid‐state ...
The objective of the review is to provide an overview of the nomenclature used in the solid-state continuum and relate these to the development ...
A Review of Disintegration Mechanisms and Measurement ...
... identify, measure and quantify the complex mass ... Towards physico-relevant dissolution testing: the importance of solid-state analysis in dissolution.
Polymorph screening in pharmaceutical development
Analysis and characterisation of solid forms · Fingerprint polymorphs from chemical shifts · Determine Z' (number of unique formula units in unit ...
Control and Selection of API Solid State Attributes
Fundamentally, the role of the solid-state chemistry team is to identify a target solid form that has the optimal physical properties, as ...