A deterministic map of Waddington's epigenetic landscape for cell ...

The image of the "epigenetic landscape", with a series of branching valleys and ridges depicting stable cellular states and the barriers ...

Mapping Waddington's epigenetic landscape. (A) The "epigenetic landscape" proposed by Conrad Waddington shows a ball rolling down valleys separated by ridges on ...

A deterministic map of Waddington's epigenetic landscape for cell ...

This quantitative map of the epigenetic landscape underlying cell fate choice provides mechanistic insights into the "forces" that direct ...

A deterministic map of Waddington's epigenetic landscape for cell ...

The image of the "epigenetic landscape", with a series of branching valleys and ridges depicting stable cellular states and the barriers between those ...

A deterministic map of Waddington's epigenetic landscape for cell ...

Specifically, we simplify a high-dimensional epigenetic landscape into a collection of discrete states corresponding to stable cell phenotypes connected by ...

Mapping Waddington's epigenetic landscape. (A) The...

In stem cell and developmental biology snapshot data allow us to characterize how the transcriptional states of cells change between successive cell types. Here ...

A deterministic map of Waddington's epigenetic ... - Altmetric

A deterministic map of Waddington's epigenetic landscape for cell fate specification. Overview of attention for article published in BMC Systems Biology, May ...

Waddington's Epigenetic Landscape, History of - Semantic Scholar

A deterministic map of Waddington's epigenetic landscape for cell fate specification · S. BhattacharyaQiang ZhangM. Andersen. Biology. BMC Systems Biology. 2011.

Not just a colourful metaphor: modelling the landscape of cellular ...

... Waddington as a metaphor of cellular development ... A deterministic map of Waddington's epigenetic landscape for cell fate specification.

Noise distorts the epigenetic landscape and shapes cell-fate decisions

Waddington's epigenetic landscape has become more than just a metaphor for cellular differentiation and developmental biology. In recent years ...

NetLand: quantitative modeling and visualization of Waddington's ...

AbstractSummary. Waddington's epigenetic landscape is a powerful metaphor for cellular dynamics driven by gene regulatory networks (GRNs). Its quantitative.

Transform the Information Landscape: Applying Waddington ...

A deterministic map of waddington's epigenetic landscape for cell fate specification. BMC systems biology , 5:85, 2011. doi: 10.1186/1752 ...

Cell fate commitment and the Waddington landscape model

The Waddington's epigenetic landscape model, a) in normal development, b) during pluripotent reprogramming, and c) direct conversion. It is now known that cells ...

Conrad Hal Waddington's methodological impact on the life sciences

Bhattacharya et al. A deterministic map of Waddington's epigenetic landscape for cell fate specification. BMC Systems Biology. (2011). P.F. Bundgaard et al ...

Waddington's Epigenetic Landscape, History of | CoLab

One of his greatest achievements was the model of the epigenetic landscape (1956, 1957): cell fate in embryological development is visually represented as a ...

Reprogramming, oscillations and transdifferentiation in epigenetic ...

Waddington's epigenetic landscape provides a phenomenological understanding of the cell differentiation pathways from the pluripotent to ...

Epigenetic Landscape Models: The Post-Genomic Era - bioRxiv

Gilbert SF (1991) Epigenetic landscaping: Waddington's use of cell ... A deterministic map of Wadding- ton's epigenetic landscape for cell fate specification.

Quantitative Modelling of the Waddington Epigenetic Landscape

... A deterministic map of Waddington's epigenetic landscape for cell fate specification. BMC Syst Biol 5:85; Li C, Wang J (2013) Quantifying cell fate decisions ...

Transition states and cell fate decisions in epigenetic landscapes

A deterministic map of Waddington's epigenetic landscape for cell fate specification · S. BhattacharyaQiang ZhangM. Andersen. Biology. BMC Systems Biology. 2011.

Modeling the epigenetic attractors landscape: toward a post ...

A deterministic map of Waddington's epigenetic landscape for Cell fate specification. BMC Syst. Biol. 5:85. doi: 10.1186/1752-0509-5-85. PubMed Abstract ...