A longitudinal study of polygenic score and cognitive function ...

We aimed to evaluate the impact of a polygenic score for general cognition on cognition decline rate, while considering baseline cognition and lifestyle ...

Conclusions: Polygenic score predicted cognition changes in addition to measured cognition. Physical activity offset genetic risk for cognition ...

A longitudinal study of polygenic score and cognitive function ...

Genomic study of cognition decline while considering baseline cognition and lifestyle behaviors is scarce. We aimed to evaluate the impact of a polygenic ...

(PDF) A longitudinal study of polygenic score and cognitive function ...

After further adjusting for the average cognition assessed in 3 visits around baseline, the polygenic score was still positively associated with ...

[PDF] A longitudinal study of polygenic score and cognitive function ...

Polygenic score predicted cognition changes in addition to measured cognition among participants with diabetes, and physical activity offset the genetic ...

Associations Between Polygenic Scores for Cognitive and Non ...

The largest association was with crystallized intelligence, mirroring a prior ABCD study where researchers found that an intelligence PGS was most predictive of ...

The relational genomics of cognitive function: A longitudinal study.

... Study, nationally representative of U.S. adults over 50. Measures included cognitive function as well as separate polygenic scores for cognition and for ...

The relational genomics of cognitive function: A longitudinal study

A recent GWAS, for instance, yielded thirteen genome-wide significant SNPs linked to cognitive function (Davies et al., 2015). A polygenic score (PGS) ...

The role of Alzheimer's disease polygenic risk scores in changes of ...

The role of Alzheimer's disease polygenic risk scores in changes of cognitive function in older adults: A longitudinal cohort study.

Polygenic predictors of age-related decline in cognitive ability - Nature

Polygenic scores can be used to distil the knowledge gained in genome-wide association studies for prediction of health, lifestyle, ...

A longitudinal study of polygenic score and cognitive function ... - OUCI

A longitudinal study of polygenic score and cognitive function decline considering baseline cognitive function, lifestyle behaviors, and diabetes among ...

Association of Cognitive Polygenic Index and Cognitive ... - MDPI

Genome-wide association studies have discovered common genetic variants associated with cognitive performance. Polygenic scores that ...

Investigating the Association Between Polygenic Risk Scores for ...

The study found that higher polygenic risk was strongly associated with higher rates of decline in memory and executive function. This was shown ...

Genetic effects on longitudinal cognitive decline during the early ...

In the Swedish BioFINDER study, we used polygenic scores (PGS) (for AD, intelligence, and educational attainment) to predict longitudinal ...

Polygenic risk scores for Alzheimer's disease in relation to cognitive ...

However, few studies have examined the effect of AD-PRS beyond the APOE gene, and the influence of genetic variants related to level of cognitive ability (COG- ...

Pathway-specific polygenic scores for Alzheimer's disease are ...

Genome-wide association studies have identified multiple Alzheimer's disease risk loci with small effect sizes. Polygenic risk scores, which ...

Apolipoprotein E moderates the association between non‐APOE ...

Variation in preclinical cognitive decline suggests additional genetic factors related to Alzheimer's disease (eg, a non-APOE polygenic risk ...

Polygenic Score Models for Alzheimer's Disease - Frontiers

Specifically, a PRS study conducted by Marden et al. (2014) suggests that AD polygenic risk might modulate both baseline memory and its rate of decline in ...

The Role of Polygenic Score and Cognitive Activity ... - ResearchGate

Request PDF | The Role of Polygenic Score and Cognitive Activity in Cognitive Functioning Among Older Adults | Background and objectives: This study ...

The long-term effects of a polygenetic predisposition to general ...

Polygenic predisposition was measured with polygenic scores for general cognition (GC-PGS). Cognition was measured employing tests for verbal ...