A mathematical investigation of the circadian clock and ...

A mathematical investigation of the circadian clock and ... - Penn Math

The mammalian circadian clock drives 24-hour rhythms in many important physiological processes, such as the sleep-wake cycle and hormone regulation.

We have created a mathematical model of the influences of the circadian clock on dopamine based on experimental findings. Our model predicts ...

A mathematical model of circadian rhythms and dopamine

There is a long history of contributions of modeling to the study of circadian rhythms: (1) Mathematical models at the single-cell level have ...

A mathematical model of circadian rhythms and dopamine - PubMed

Our mathematical model can be used for further investigations of the effects of the mammalian circadian clock on the dopaminergic system.

A Mathematical Model of the Liver Circadian Clock Linking Feeding ...

Research Support, Non-U.S. Gov't. MeSH terms. Adenosine Monophosphate / metabolism; Adenylate Kinase / metabolism; Animals; Circadian Clocks / ...

Wanasingha, Nayana - OhioLINK ETD

Mathematical modeling of circadian systems has guided ... circadian systems and eventually assist studies related to circadian rhythm disorders.

A mathematical model of the circadian clock and drug pharmacology ...

Such results highlight the need for more research in this field to understand inter-patient discrepancies and enable safe and efficient clinical application of ...

(PDF) A mathematical model of circadian rhythms and dopamine

Our mathematical model can be used for further investigations of the effects of the mammalian circadian clock on the dopaminergic system. The ...

Mathematical modeling of circadian rhythms - Asgari‐Targhi - 2019

Mathematical models of circadian rhythms have been proposed to provide a better understanding of and to predict aspects of this complex ...

A mathematical model of melatonin synthesis and interactions with ...

Finally, in Section 3.4 we study how the dosing of melatonin can cause phase shifts in the circadian clock and compare to experimental data. Section snippets.

Mathematical Modeling and Analysis of Cellular Clocks.

Abstract. Cells generate various biological rhythms that control important aspects of cell physiology including circadian (daily) events, cell division, ...

A new model shows how to better synchronize our internal clocks

... circadian system, the researchers said. They emphasized that the study results are from computer simulations of the mathematical model ...

Mathematical Modeling in Circadian Rhythmicity - SpringerLink

Simple generic models are useful to study general properties of circadian rhythms, such as coupling of large oscillator ensembles [10, 11], ...

Modelling Circadian Rhythms in Drosophila and Investigation of VRI ...

We present a brief review of molecular biological basis and mathematical modelling of circadian rhythms in Drosophila. We discuss pertinent aspects of a new ...

Mathematical Analysis of Robustness of Oscillations in Models of the ...

A number of mathematical models have been developed to study features of the circadian clock in a variety of organisms. In this paper, we use ...

Mathematical modeling of temperature-induced circadian rhythms

... studies of circadian rhythms (Nudell et al., 2019). Unlike biochemical signals, external temperature rhythms can be modulcated at will and provide a more ...

theoretical investigation on models of circadian rhythms based on ...

2010 Mathematics Subject Classification. Primary: 34Cxx; Secondary: 92Bxx. Key words and phrases. Circadian rhythm, positive feedback, steady state, limit cycle ...

Optimal adjustment of the human circadian clock in the real world

Previous research has used mathematical models to compute light schedules that shift the circadian clock to a new time zone as quickly as ...

Some Mathematical Questions in Biology—Circadian Rhythms

AMS, American Mathematical Society, the tri-colored AMS logo, and Advancing research, Creating connections, are trademarks and services marks of the American ...

Math Reveals The Link Between The Body Clock And Cancer

... circadian clock and cancer, paving the way for better anti-cancer drug research. SHARE. SHARE · tweet · share. AsianScientist (Dec. 1, 2016) ...