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A multi|ethnic polygenic risk score is associated with hypertension ...


A multi-ethnic polygenic risk score is associated with hypertension ...

In a multi-stage analysis of 52436 individuals aged 17-90 across diverse cohorts and biobanks, we train, test, and evaluate a polygenic risk ...

Abstract MP18: A Multi-ethnic Polygenic Risk Score Is Associated ...

The HTN-PRS was associated with prevalent hypertension (OR=1.76, 95% CI [1.70, 1.83], per one standard deviation (SD) of the PRS) across all ...

A multi-ethnic polygenic risk score is associated with hypertension ...

Polygenic Risk Scores (PRS) estimate the effect of many genetic variants on an individual's genetic susceptibility to a disease or trait, typically calculated ...

A multi-ethnic polygenic risk score is associated with hypertension ...

A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood ... polygenic risk score (PRS) for ...

A multi-ethnic polygenic risk score is associated with hypertension ...

A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood ; I have followed instructions for TOPMed ...

Polygenic risk scores associate with blood pressure traits across the ...

Since the consequences of high BP generally occur after the reproductive years, BP-related SNPs are less susceptible to negative selection ...

Evaluating the use of blood pressure polygenic risk scores across ...

We assess performance and limitations of polygenic risk scores (PRSs) for multiple blood pressure (BP) phenotypes in diverse population ...

A multi-ethnic polygenic risk score is associated with hypertension ...

Genome sequencing for "NHLBI TOPMed: Multi-Ethnic Study of Atherosclerosis" (phs001416.v2.p1) was performed at the Baylor College of Medicine ...

A multi-ethnic polygenic risk score is associated with hypertension ...

A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood · Overview · Fingerprint ...

Polygenic Risk Scores | Tamar Sofer Lab

Kurniansyah N, Goodman MO, Kelly TN, Elfassy T, Wiggins KL, Bis JC, et al. A multi-ethnic polygenic risk score is associated with hypertension prevalence ...

Blood Pressure Polygenic Risk Score Associated with ...

A polygenic risk score aggregates the risk associated with many common DNA sequence variants into a single factor. The current study examined a ...

Association of a Multiancestry Genome-Wide Blood Pressure ...

A polygenic risk score (PRS) aggregates the risk conferred by multiple common DNA sequence variants into a single predictor, and a BP PRS can be ...

(PDF) A multi-ethnic polygenic risk score is associated with ...

The HTN-PRS was associated with prevalent hypertension (OR=2.10, 95% CI [1.99, 2.21], per one standard deviation (SD) of the PRS) across all ...

A multi-ethnic polygenic risk score is associated with hypertension ...

Abstract BackgroundWe used summary statistics from previously-published GWAS of systolic and diastolic BP and of hypertension to construct Polygenic Risk ...

A multi-ethnic polygenic risk score is associated with hypertension ...

Wiggins & Joshua C. Bis & Xiuqing Guo & Walter Palmas & Kent D. Taylor & Henry J. Lin & Jeffrey Haessler & Yan Gao , 2022. "A multi-ethnic polygenic risk score ...

Life-Course Associations between Blood Pressure-Related ... - MDPI

The multi-ancestry genome-wide polygenic risk scores (PRSs) for systolic BP (SBP), diastolic BP (DBP), and hypertension were tested for an association with ...

A multi-ethnic polygenic risk score is associated with hypertension ...

In a multi-stage analysis of 52436 individuals aged 17-90 across diverse cohorts and biobanks, we train, test, and evaluate a polygenic risk score (PRS) for ...

Study uncovers the role of polygenic risk scores in hypertension ...

The genetic predisposition to hypertension was quantified using a previously validated systolic blood pressure polygenic risk score. The ...

A multi-ethnic polygenic risk score is associated with hypertension ...

In a multi-stage analysis of 52436 individuals aged 17-90 across diverse cohorts and biobanks, we train, test, and evaluate a polygenic risk score (PRS) for ...

Utility of a Systolic Blood Pressure Polygenic Risk Score With ...

This genetic association study uses data from Black participants in the the Genetics of Hypertension Associated Treatments (GenHAT) study to ...