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A multi|targeting immunotherapy ameliorates multiple facets of ...


A multi-targeting immunotherapy ameliorates multiple facets of ...

In this study, we present a dual AD vaccine combining Aβ and pTau vaccines, eliciting robust and enduring antibody responses against pathological Aβ and pTau ...

A multi-targeting immunotherapy ameliorates multiple facets of ...

This innovative multi-targeting immunotherapy remarkably ameliorates diverse AD pathologies, demonstrating maximum benefits in slowing the clinical progression ...

(PDF) A multi-targeting immunotherapy ameliorates multiple facets ...

PDF | Alzheimer' s disease (AD) is a intricate disorder involving amyloid deposits, neurofibrillary tangles, and chronic neuroinflammation.

(PDF) A multi-targeting immunotherapy ameliorates multiple facets ...

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Immunotherapy targeting plasma ASM is protective in a mouse ...

A multi-targeting immunotherapy ameliorates multiple facets of Alzheimer's disease in 3xTg mice. Article Open access 20 August 2024. VEGF-A in ...

Role of tumor microenvironment in cancer progression and ...

... and multi‐stage drug delivery system (MS DDS) based ... various anti‐cancer therapies, especially immunotherapy. PD‐1 and CTLA‐4‐targeting immunotherapies ...

Targeting CD73 to augment cancer immunotherapy - ScienceDirect

... multiple aspects of the immune response. Owing to its multifaceted capacity to tumor promotion as an emerging immune checkpoint, CD73 is an ...

Strategies to Overcome Failures in T-Cell Immunotherapies by ...

... multiple immune cell populations in the TME, clinical development of ... Targeting of T Regulatory Cells to Enhance Cancer Immunotherapy. Cancer Res ...

[PDF] Passive immunotherapy for N-truncated tau ameliorates the ...

This review assesses several AD mouse models from the ... Immunotherapy targeting pathological tau protein in Alzheimer's disease and related tauopathies.

Lung cancer immunotherapy: progress, pitfalls, and promises

The present article encompasses a detailed overview of the recent developments in the immunotherapeutic landscape in targeting small cell lung cancer (SCLC) ...

T-cell agonists in cancer immunotherapy

Other mechanisms for promoting antitumor T-cell function are the targeting of costimulatory molecules expressed on the surface of T cells, such as 4-1BB, OX40, ...

Rationale for anti-CD137 cancer immunotherapy - ScienceDirect

Several facts gained from preclinical studies and clinical trials (mostly ... targeting T and NK cells may occur, releasing a robust antitumour immune response.

Principles of Immunotherapy: Implications for Treatment Strategies ...

The safety and efficacy of various combinations of immune checkpoint inhibitors with cytotoxic chemotherapy (referred to as immunochemotherapy), with small- ...

Combination strategies to maximize the benefits of cancer ...

Immunotherapies such as immune checkpoint blockade (ICB) and adoptive cell therapy (ACT) have revolutionized cancer treatment, especially in ...

Spotlight on Immunotherapy: Pushing the Frontier of Cancer Medicine

Atezolizumab is a PD-L1-targeting ICI that has been approved previously for the treatment of patients with several cancer types, including liver cancer, ...

Rethinking immune checkpoint blockade: 'Beyond the T cell'

... immune cells mediate key aspects of checkpoint therapy biology. ... Lenalidomide enhances immune checkpoint Blockade-Induced immune response in multiple myeloma.

Cancer immunotherapy candidate provokes powerful dual response ...

The molecule's dual mechanism of action — targeting both tumor and immune ... many other emerging immunotherapies. The team also found that ...

Choc cytokinique - Wikipédia

Un choc cytokinique (en anglais cytokine storm, littéralement « tempête de cytokines » ou orage cytokinique) est la forme la plus grave du syndrome de ...

Novel Cancer Immunotherapies: Targeting Multiple Avenues of ...

Novel Cancer Immunotherapies: Targeting Multiple Avenues of Cancer Immune Evasion. Dr David Munn reviews the latest understanding in cancer immunotherapy ...