- A narrative review of immune checkpoint mechanisms and current ...🔍
- Review of the Immune Checkpoint Inhibitors in the Context of ...🔍
- a narrative review of immune checkpoint mechanisms🔍
- Mechanisms of immune checkpoint inhibitors🔍
- Immune checkpoint therapy—current perspectives and future ...🔍
- Immune Checkpoint Inhibitors🔍
- Immunomodulatory Precision🔍
- A Systematic Review of the Mechanisms Involved in Immune ...🔍
A narrative review of immune checkpoint mechanisms and current ...
A narrative review of immune checkpoint mechanisms and current ...
In this review, we summarise the mechanisms of the major immune checkpoint molecules and the application of selected immune checkpoint inhibitors in clinical ...
A narrative review of immune checkpoint mechanisms and current ...
A narrative review of immune checkpoint mechanisms and current immune checkpoint therapy.
Cytotoxic T lymphocyte-associated antigen-4 and programmed cell death protein 1 are the two most well- known receptors that downregulate immune ...
A narrative review of immune checkpoint mechanisms and current ...
Download Citation | On Jan 1, 2021, Siqi Peng and others published A narrative review of immune checkpoint mechanisms and current immune ...
Review of the Immune Checkpoint Inhibitors in the Context of ...
CTLA-4 inhibitors target the CTLA-4 protein, which is present in the T-cells and acts as a brake on the immune system [9]. By obstructing the ...
a narrative review of immune checkpoint mechanisms - Article List ...
A narrative review of immune checkpoint mechanisms and current immune checkpoint therapy. Ann Blood 2022;7:33. Correspondence to: Siqi Peng. Guangzhou ...
Mechanisms of immune checkpoint inhibitors - Nature
Immune checkpoints are a type of immunosuppressive molecules expressed on immune cells, which can regulate the degree of immune activation and ...
Immune checkpoint therapy—current perspectives and future ...
This review highlights the biology of anti-tumor immunity underlying response and resistance to ICT, discusses efforts to address the current ...
Immune Checkpoint Inhibitors: Fundamental Mechanisms, Current ...
... current literature on this topic, this review aims to explore in depth the basis of the use of ICIs in the treatment of advanced cancers, evaluate its ...
Immune Checkpoint Inhibitors: A Narrative Review on PD-1/PD-L1 ...
Checkpoint inhibitors have been implicated in the treatment of several cancers due to their ability to exploit the immune system's ...
Immunomodulatory Precision: A Narrative Review Exploring ... - MDPI
Most current ICIs target the molecules CTLA-4, PD-1, and PD-L1. Ipilimumab, a CTLA-4 blocker, is the first FDA-approved drug targeting an immune checkpoint to ...
A Systematic Review of the Mechanisms Involved in Immune ...
Immune checkpoint inhibitors (ICIs) are monoclonal antibodies that block CTLA-4, PD-1, or PD-L1 and induce the activation of the immune system against ...
Immune checkpoint inhibitors: a narrative review of considerations ...
Immune checkpoint inhibitors are a new type of immunotherapy drug used to treat cancer. They show promising results but are associated with immune-related ...
Immune checkpoint signaling and cancer immunotherapy - Nature
Moreover, adverse effects, such as autoimmune symptoms and tumor hyperprogression, present a significant downside in some clinical applications.
A narrative review of immune checkpoint mechanisms and current ...
A narrative review of immune checkpoint mechanisms and current immune checkpoint therapy. Siqi Peng. ,. Yifeng Bao. Show full list: 2 authors. Publication type ...
Immune checkpoint modulators in cancer immunotherapy
The discovery of immune checkpoint inhibitors (ICIs) has now been universally acknowledged as a significant breakthrough in tumor therapy ...
Novel targets for immune-checkpoint inhibition in cancer
Current data suggest that PD-1, CTLA-4, and LAG-3 upregulation limits the efficacy of single-agent immune-checkpoint inhibitors. Ongoing clinical trials are ...
Current Progress and Future Perspectives of Immune Checkpoint in ...
A number of immune checkpoint proteins were shown to be dysregulated in cancers and infectious diseases, including PD-1/PD-L1, CTLA-4, ...
Mechanisms and Management of Immune Checkpoint Inhibitor ...
Anticancer immunity consists of a series of stepwise events characterized by the cyclic coordination of numerous factors, leading to the amplification of T-cell ...
Immune mechanisms of toxicity from checkpoint inhibitors - Cell Press
In this review, we discuss our current understanding of the inflammatory toxicities from immune checkpoint inhibitors (ICIs) and propose optimal treatment ...