A new strategy to counter insulin damage in coronary artery disease

By studying blood vessel tissue from 674 patients, a research team has discovered how insulin contributes to the dysfunction of blood vessels in ...

A new approach to treating vascular insulin damage in coronary ...

A team of researchers affiliated with institutions in the UK, Greece and Germany has found a new way to treat insulin damaged blood vessels associated with ...

A New Strategy to Counter Insulin Damage in Coronary Artery ...

image: Stained images of oxygen production (red) in response to insulin treatment in blood vessel tissue from patients with atherosclerosis.

Insulin Resistance and Coronary Artery Disease - NCBI

This research analyzes the molecular processes by which insulin resistance leads to disruptions in lipid metabolism, inflammatory reactions, and ...

Emerging targets for cardiovascular disease prevention in diabetes

Modeling and pharmacology-based approaches to improve insulin action provide additional potential strategies to combat CVD. The development of new strategies ...

Strategies for chronic coronary disease: A brief guide for clinicians

The analysis ultimately demonstrated that in patients with CCD, SGLT-2 inhibitors significantly reduced cardiovascular events compared with the ...

Management of Stable Coronary Artery Disease in Patients with ...

The scientific statement includes emphasis on the new role of sodium-glucose cotransporter-2 (SGLT-2) inhibitors and glucagon-like peptide-1 ( ...

Insulin resistance and cardiovascular disease - Sage Journals

Insulin resistance (IR) and cardiovascular disease (CVD) represent two universal public health hazards, especially in today's Western societies.

Insulin Resistance and Your Heart - WebMD

A one-point rise in your A1c, the blood test that measures blood sugar levels over time, can boost your chances of having cardiovascular disease ...

Review Insulin Resistance, Hyperglycemia, and Atherosclerosis

Progress in preventing atherosclerotic coronary artery disease (CAD) has been stalled by the epidemic of type 2 diabetes.

Primordial Drivers of Diabetes Heart Disease

Numerous studies have shown that insulin resistance can affect blood circulation and myocardium, which indirectly cause cardiac hypertrophy and ...

Insulin Resistance and Atherosclerosis - Oxford Academic

Multiple studies have demonstrated that insulin resistance is a strong predictor of atherosclerotic cardiovascular (CV) disease (ASCVD).

Clinical Management of Stable Coronary Artery Disease in Patients ...

Taken together, these trials suggest that the general strategy of targeting HbA1c levels to <6.5% among patients with T2DM does not reduce the ...

Insulin treatment in patients with diabetes mellitus and heart failure ...

Insulin is frequently used in these patients, but its benefit/risk ratio is still not clear, particularly since new antidiabetic drugs that reduce major adverse ...

Cardiovascular Disease and Diabetes - American Heart Association

Physical inactivity is another modifiable risk factor for insulin resistance and CVD. Exercising and losing weight can prevent or delay the ...

Diabetes care: 10 ways to avoid complications - Mayo Clinic

... damage and heart disease — as well as screen for other medical problems. He ... High blood sugar can reduce blood flow and damage the nerves in your feet.

Diabetic vascular diseases: molecular mechanisms and therapeutic ...

Basic pharmacological therapy for CAD in patients with diabetes includes antiplatelet, cholesterol-lowering, anti-myocardial ischemia strategies ...

Association between insulin resistance and the development of ...

For many years, cardiovascular disease (CVD) has been the leading cause of death around the world. Often associated with CVD are ...

Management of coronary artery disease: therapeutic options in ...

Diabetic patients with CAD are predisposed to higher cardiovascular events after balloon angioplasty. Whether stenting and new antiplatelet drugs improve the ...

A Randomized Trial of Therapies for Type 2 Diabetes and Coronary ...

Among patients with diabetes, studies have indicated that increased insulin levels predict adverse outcomes and that control of hyperglycemia by ...