A novel in|vitro model of intervertebral disc degeneration using ...

A novel in-vitro model of intervertebral disc degeneration using ...

Intervertebral disc (IVD) degeneration includes changes in tissue biomechanics, physical attributes, biochemical composition, disc microstructure, ...

A novel in-vitro model of intervertebral disc degeneration using ...

The rheological analysis revealed the pre-gel viscoelastic and shear-thinning characteristics. Results In vitro, cell viability was maintained ...

A Novel Model for Intervertebral Disc Degeneration Using Whole ...

Intervertebral disc (IVD) disorders resulting in pain and disability are extremely prevalent and current treatment options do not restore tissue integrity ...

Development of a novel model of intervertebral disc degeneration by ...

Although, the pathology of intervertebral disc (IVD) degeneration has been modeled using various biological methods, these models are ...

In-vitro models of disc degeneration – A review of methods and ...

The intervertebral disc (IVD) provides flexibility, acts as a shock absorber, and transmits load. Degeneration of the IVD includes alterations in the ...

Development of a novel model of intervertebral disc degeneration by ...

In this study, we investigated the pathophysiological changes in spinal structures associated with the development of pain and IVD degeneration induced by MIA ...

In vitro model of distinct catabolic and inflammatory response ...

... through the microfluidic platform. These results suggest that AF cells may play a major role in the initial degeneration of intervertebral disc ...

Constructing intervertebral disc degeneration animal model - Frontiers

Intervertebral disc degeneration (IDD) is one of the major causes of LBP (5–7). Approximately 40% of LBP presented with the feature of IDD (8). The ...

Development of an in vitro model to test the efficacy of novel ...

Intervertebral Disc Degeneration · 100% ; Intervertebral Disk Degeneration · 100% ; Proteoglycan · 66% ; Explant · 33% ; Cell Activity · 33%.

In-vitro models of disc degeneration – A review of methods ... - OUCI

Emanuel, K.S., Vergroesen, P.-P.A., Peeters, M., Holewijn, R.M., Kingma, I., Smit, T.H., 2015. Poroelastic behaviour of the degenerating human intervertebral ...

A novel in-vitro model of intervertebral disc degeneration using ...

Article on A novel in-vitro model of intervertebral disc degeneration using hyperphysiological loading, published in Journal of Biomechanics ...

A novel in vivo porcine model of intervertebral disc degeneration ...

CONCLUSIONS:Imaging and histological analysis showed that disc cryoinjury applied through endplate perforation was superior to the classical NeP and EP models ...

A Review of Animal Models of Intervertebral Disc Degeneration ...

Human intervertebral disc degeneration is a complex and incompletely understood multifactorial process with contributions from genes, mechanical ...

3D assessment of intervertebral disc degeneration in zebrafish ...

Our findings suggest a U-shaped model to explain the relationship between BMD and IVDD. Genetic factors regulating bone formation, resorption ...

Intervertebral disc degeneration—Current therapeutic options and ...

Basketball, baseball, swimming, and soccer were linked to better IVD parameters over controls, while poorer NP hydration was marginally linked with a longer ...

Mechanics and Biology Interact in Intervertebral Disc Degeneration

The COM produced a reproducible severe IVDD model with characteristics of sparse vertebral trabeculae, cartilaginous EP ossification, ...

(PDF) A novel in vitro senescent model of intervertebral disc ...

Background Nucleus pulposus cell (NPCs) senescence within degenerative intervertebral discs is associated with the occurrence and progression of ...

In vivo experimental intervertebral disc degeneration induced by ...

Recently, biological therapies for early intervention of degenerative disc disease have been introduced and developed; however, a functional ...

Novel therapeutic strategies for degenerative disc disease

A similar rabbit model of degenerated IVD with PRP injections also led to significant restoration of disc height and recruitment of chondrocyte- ...

A novel in vitro senescent model of intervertebral disc degeneration ...

Abstract Background Nucleus pulposus cell (NPCs) senescence within degenerative intervertebral discs is associated with the occurrence and progression of ...