A review of cytokine|based pathophysiology of Long COVID symptoms

A review of cytokine-based pathophysiology of Long COVID symptoms

Varied and relapsing symptoms of Long COVID can be attributed to elevated peripheral and central cytokines, generated by an abnormal immune response.

A review of cytokine-based pathophysiology of Long COVID symptoms

We propose a description of the pathophysiology of the Long COVID presentation based on inflammatory cytokine cascades and the p38 MAP kinase signaling ...

A Cytokine-based model for the pathophysiology of Long COVID ...

Dysregulated immune-inflammatory response with elevated peripheral and central cytokines can explain Long COVID symptoms. Hyperreactive brain microglia can ...

A Cytokine-based model for the pathophysiology of Long COVID ...

There are abundant similarities between symptoms in Long COVID and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). A post- ...

Long COVID: major findings, mechanisms and recommendations

Although COVID-19 was initially recognized as a respiratory illness, SARS-CoV-2 has capability to damage many organ systems. The damage that has ...

Mechanisms of long COVID: An updated review - ScienceDirect.com

Dysregulated resident T cells have been shown to be associated with lung inflammation, pathology, and fibrosis after respiratory viral infection, particularly ...

A review of cytokine-based pathophysiology of Long COVID symptoms

DNA polymorphisms and viral-induced epigenetic changes to cytokine gene expression may lead to chronic inflammation in Long COVID patients, predisposing some to ...

Pathophysiological, immunological, and inflammatory features of ...

Like the acute phase, long COVID exhibits a multi-systemic nature (108, 109, 116). Two primary symptom patterns typically emerge in long COVID cases (1): ...

Exploring the Pathophysiology of Long COVID: The Central Role of ...

Long COVID (LC), also referred to as Post COVID-19 Condition, Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), and other terms, represents a complex ...

Mechanisms of long COVID and the path toward therapeutics: Cell

Here, we review the current state of knowledge regarding the biology and pathophysiology of long COVID, focusing on how the proposed mechanisms ...

Full article: Pathophysiology and mechanism of long COVID

The mechanisms underlying its pathophysiology are still unclear. Although organ damage from the acute infection phase likely accounts for symptoms, specific ...

Distinguishing features of long COVID identified through immune ...

... of these symptoms are unclear. Here 275 individuals with or without long COVID were enrolled in a cross-sectional study that included ...

Mechanisms of long COVID and the path toward therapeutics

Here, we review the current state of knowledge regarding the biology and pathophysiology of long COVID, focusing on how the proposed mechanisms ...

Unraveling Links between Chronic Inflammation and Long COVID

Richard Becker discussed how SARS-CoV-2 infection triggers a distinct acute and multiorgan inflammatory response. The severity of acute COVID-19 ...

Long COVID-19 Pathophysiology: What Do We Know So Far? - MDPI

A possible mechanism for this is dysautonomia in either brain regions or intrathoracic receptors [38,50]. The respiratory long COVID-19 symptoms can also be ...

Clues to causes of long COVID - @theU - The University of Utah

Like the earlier researchers, the U of U Health scientists suspected that abnormal and elevated levels of cytokines were a driving force behind ...

What is really 'Long COVID'? | Inflammopharmacology

The pathogenesis of long COVID syndrome is poorly understood, but initial and persistent vascular endothelial injury that often triggers the ...

a narrative review of the clinical aftermaths of COVID-19 with a focus ...

Still, to this day, the causative pathophysiological mechanisms of long COVID remain to be elucidated, with long-term organ damage, immune system dysregulation ...

Long COVID: a clinical update - The Lancet

Long COVID can affect multiple organ systems and lead to severe and protracted impairment of function as a result of organ damage. The burden of this disease, ...

A review of cytokine-based pathophysiology of Long COVID symptoms

Keywords ### #COVID19 #cytokines #LongCOVID #neuroinflammation #postacutesequelaeofCOVID19 #MyalgicEncephalomyelitis(ME) #RTCLTV #shorts ...