A review of the cost|effectiveness of genetic testing for germline ...

A review of the cost-effectiveness of genetic testing for germline ...

Germline testing for HBOC was likely to be cost-effective across most settings, except when used as a co-dependent technology with the PARP inhibitor, ...

A review of the cost-effectiveness of genetic testing for germline ...

Citation saw a substantial drop in testing costs (US$200) and the ICER for population-wide testing versus testing those with high-risk was US$132,200/QALY. The ...

A review of the cost-effectiveness of genetic testing for germline ...

Objective: To systematically review economic evaluations on cost-effectiveness of germline testing in breast, ovarian, or colorectal cancer.

A review of the cost-effectiveness of genetic testing for germline ...

Conclusions Targeted BRCA or multiple gene screening is likely to be cost-effective. Methodological variations could be decreased by the ...

A review of the cost-effectiveness of genetic testing for germline ...

Conclusion: Germline testing for HBOC was likely to be cost-effective across most settings, except when used as a co-dependent technology with ...

A Cost-Effectiveness Evaluation of Germline BRCA1 and BRCA2 ...

Probabilistic sensitivity analysis showed that the probability of germline BRCA mutation testing being cost-effective at a threshold of £20,000/QALY was 99.9%.

The Cost-Effectiveness of Germline BReast CAncer Gene Testing in ...

Our evaluation suggests that germline BReast CAncer gene testing-guided treatment with PARP in mPCa is not cost-effective when restricted to the ...

Economic evaluation of germline genetic testing for breast cancer in ...

This study aims to systematically review economic evaluations and the quality of selected studies involving genetic screening strategies for BC in low and ...

A review of the cost-effectiveness of genetic testing for germline ...

Type. Journal Article ; Title. A review of the cost-effectiveness of genetic testing for germline variants in familial cancer ; Author Name(s). Srinivas Teppala.

Cost-effectiveness analysis of universal germline testing for patients ...

The ICER was $121,942/LY. Using a willingness-to-pay of $100,000/LY, selective germline genetic testing based on a positive family history of PC was more cost- ...

Cost-Effectiveness of Gene-Specific Prevention for Ovarian and ...

... germline and parallel somatic genetic testing in epithelial ovarian cancer: SIGNPOST Study. ... A Systematic review on cost-effectiveness studies ...

The Cost-Effectiveness of Germline BReast CAncer Gene Testing in ...

Keywords: BRCA, cascade testing, genetic testing, germline testing, metastatic prostate cancer. VALUE HEALTH. 2024; -(-):-–-. Introduction. Prostate cancer (PCa) ...

Mainstream germline genetic testing for patients with epithelial ...

Based on these costs, the genetics-related healthcare costs after implementing our mainstream genetic testing pathway were €2.418,41 per patient, which is a 31% ...

Cost-Effectiveness of Multigene Testing for Breast and Ovarian Cancer

Population-wide genetic testing was 100% cost-effective for all the simulations in probabilistic sensitivity analyses; it became cost- ...

Guidelines for genetic testing in prostate cancer: a scoping review

A review of the cost-effectiveness of genetic testing for germline variants in familial cancer. Journal of Medical Economics. 2022 https ...

Selection of Germline Genetic Testing Panels in Patients With Cancer

Ninety percent of VUS results will be reclassified as benign, and a small proportion will be reclassified as pathogenic, impacting clinical ...

A review of the cost-effectiveness of genetic testing for germline ...

Germline testing could be considered as cost-effective compared to no testing in Upper MICs (e.g., Malaysia, China, Brazil) but not in Lower MICs (e.g., India) ...

Cost-effectiveness of population-wide genomic screening for Lynch ...

Using historical genetic testing costs of $500 and $1000, the incremental cost of screening increased to $53.2 million and $101 million, respectively, and the ...

Few People with Cancer Undergo Germline Testing - NCI

Testing among people with other cancers possibly associated with germline gene mutations was much less common. About 6% of people with ...

Meeting the need for germline testing - The Lancet Oncology

Germline genetic testing for pathogenic mutations in people diagnosed with cancer is recommended for several cancer types and has been shown to have a positive ...