A sustained CYCLINB1

A sustained CYCLINB1;1 and STM expression in the neoplastic ...

A sustained CYCLINB1;1 and STM expression in the neoplastic tissues induced by Rhodococcus fascians on Arabidopsis underlies the persistence of the leafy gall ...

Aneuploidy in Oocytes Is Prevented by Sustained CDK1 Activity ...

Successful mitosis requires that cyclin B1:CDK1 kinase activity remains high until chromosomes are correctly aligned on the mitotic spindle.

Cyclin B1 - an overview | ScienceDirect Topics

The cyclins are a family of proteins that are centrally involved in cell-cycle regulation and are structurally identified by conserved “cyclin box” regions.

Aneuploidy in Oocytes Is Prevented by Sustained CDK1 Activity ...

elucidate how an excess of cyclin B1 preserves CDK1 activity to assist the spindle checkpoint to prevent segregation errors in mouse oocytes.

Cyclin B1 - an overview | ScienceDirect Topics

A large number of proteins are phosphorylated by the cyclin B1–Cdk1 complex prior to mitotic entry, which initiates the mitotic events, including nuclear ...

Sustained Spindle-Assembly Checkpoint Response Requires De ...

The exogenous expression of Cyclin B1 substantially rescued the mitotic phenotype in nocodazole cells treated with the inhibitors of transcription and ...

Downregulation of G2/mitotic-specific cyclinB1 triggers autophagy ...

CyclinB1 is a regulatory protein involved in mitosis. Multiple lines of evidence indicate that cyclinB1 depletion constrains proliferation ...

Dose‐dependent effects of stable cyclin B1 on progression through ...

... cyclinB1 did not block anaphase. Surprisingly, stable cyclinB1 maintained a bipolar spindle, with anaphase chromosomes positioned near the cellular equator.

Cell cycle-dependent binding between Cyclin B1 and Cdk1 ...

Thus, a combination of FCS imaging with CRISPR/Cas9-mediated gene editing offers a platform to study the rapid dynamics of protein complex ...

Cyclin B1–Cdk1 Activation Continues after Centrosome Separation ...

When active, the enzyme cyclin B1–cyclin-dependent kinase 1 (Cdk1) commits a growing cell to the process of mitotic cell division and chromosome separation.

Cyclin B1-Cdk1 facilitates MAD1 release from the nuclear pore to ...

The rapid and complete reorganization of a cell at mitosis is one of the most striking events in cell biology, but we are only just ...

p21-Mediated Nuclear Retention of Cyclin B1-Cdk1 in Response to ...

Therefore, in normal cells, p21 exerts a dual role in mediating DNA damage-induced cell cycle arrest and exit before mitosis. In addition to blocking pRb ...

Downregulation of cyclin B1 induced a sustained apoptosis. (A) Cells...

(B) Apoptosis induction in HeLa 776-6 cells was further detected with bisbenzimide staining. Typical apoptotic morphologies of DNA were displayed, such as ...

Inactivation of M-Phase Promoting Factor at Exit from First ...

... cyclin B1, a sustained high MPF activity, and recession of embryonal mitosis. ... Surprisingly, in our present study inhibition of cyclin B1 degradation did not ...

Targeting cyclin B1 inhibits proliferation and sensitizes breast ...

Uncontrolled cell proliferation, which is associated with the loss of the proper cell cycle control, is a prominent feature in these cancers.

Cyclin B1 stability is increased by interaction with BRCA1, and its ...

Germline BRCA1 mutations predispose women to breast and ovarian cancer. BRCA1, a large protein with multiple functional domains, ...

Cyclin B1 scaffolds MAD1 at the kinetochore corona to activate the ...

The spindle assembly checkpoint controls anaphase onset and inactivation of the key mitotic kinase, Cyclin B1‐CKD1. A surprising new structural ...

A sustained CYCLINB1;1 and STM expression ... - BVS

A sustained CYCLINB1;1 and STM expression in the neoplastic tissues induced by Rhodococcus fascians on Arabidopsis underlies the persistence of the leafy ...

Anti-Cyclin B1 Antibody, clone GNS3 (8A5D12) | 05-373

Anti-Cyclin B1 Antibody, clone GNS3 (8A5D12) is a Mouse Monoclonal Antibody for detection of Cyclin B1 also known as G2/mitotic-specific cyclin B1 & has ...

Nuclear-cytoplasmic compartmentalization promotes robust timing of ...

Upon cyclin B1-Cdk1 activation, the sensor domain is phosphorylated by Cdk1 and bound by the ligand domain, thereby inducing a conformational ...