ATP|stimulated interaction between epidermal growth factor ...

ATP-stimulated interaction between epidermal growth factor ...

The receptor for epidermal growth factor (EGF) has been identified as a transmembrane glycoprotein that has tyrosine-specific kinase activity.

Extracellular ATP-induced regulation of epidermal growth factor ...

We investigated the effect of extracellular ATP on the interaction of epidermal growth factor (EGF) with its receptor in cultured renal epithelial cells, LLC- ...

Epidermal growth factor–stimulated Akt phosphorylation requires ...

Epidermal growth factor (EGF) binding to its receptor (EGFR) activates several signaling intermediates, including Akt, leading to control of cell survival and ...

Controlling Epidermal Growth Factor (EGF)-stimulated Ras ...

Epidermal growth factor (EGF)-stimulated Ras activation involves specific interactions between the EGF receptor (EGFR), the adaptor proteins Grb2 and Shc, ...

Unliganded Epidermal Growth Factor Receptor Dimerization ...

These data suggest that EGFR dimerization can be induced by the interaction of quinazolines at the ATP site in the absence of receptor ligand binding. In SKBR-3 ...

Nucleotide Binding by the Epidermal Growth Factor Receptor ...

TNP-ATP was found to be an active substrate for the autophosphorylation reaction of the recombinant EGF receptor protein-tyrosine kinase domain (TKD).

stimulated Ras Activation in Intact Cells by a Cell-permeable ...

Epidermal growth factor (EGF)-stimulated Ras activation involves specific interactions between the EGF receptor (EGFR), the adaptor proteins Grb2 and Shc ...

extracellular signal-stimulated nuclear–cytoplasmic export and ...

EGF triggers dephosphorylation of the mRNA-binding protein Grb7 in the nucleus, leading to its export, and it also stimulates FAK, which rephosphorylates G.

Epidermal Growth Factor Receptor–Stimulated Intestinal Epithelial ...

Inhibition of EGF receptor tyrosine kinase activ- ity, phospholipase C, or phosphatidylinositol 3-kinase attenuated EGF-induced intestinal cell migration. Pre-.

Transforming Growth Factor B1 Stimulated DNA Synthesis in the ...

EGF via MAPK3/1 maintained functional levels of CCND2 through CCND2 synthesis as well as degradation. EGF and TGFB1 together inhibited CDK4 activation and DNA ...

Coordinated Traffic of Grb2 and Ras during Epidermal Growth ...

Stimulation of cells by EGF resulted in the accumulation of large pools of Grb2-CFP and YFP-Shc in endosomes, where these two adaptor proteins formed a complex ...

EGFR - Epidermal growth factor receptor - Homo sapiens (Human)

Positively regulates cell migration via interaction with CCDC88A/GIV which retains EGFR at the cell membrane following ligand stimulation, promoting EGFR ...

Extracellular ATP-induced regulation of epidermal growth factor ...

-We investigated the effect of extracel- lular ATP on the interaction of epidermal growth factor (EGF) with its receptor in cultured renal epithelial cells, LLC ...

Extracellular ATP-induced regulation of epidermal growth factor ...

Mentioning: 7 - We investigated the effect of extracellular ATP on the interaction of epidermal growth factor (EGF) with its receptor in cultured renal ...

Molecular mechanisms of ATP-dependent transactivation and EGF ...

Download scientific diagram | Molecular mechanisms of ATP-dependent transactivation and EGF-dependent direct activation of EGFR. A, ATP-mediated stimulation ...

ATP-Mediated Transactivation of the Epidermal Growth Factor ...

ATP-mediated EGFR transactivation in airway epithelial cells was found to involve purinergic P2Y2 receptor stimulation, and both ligand-dependent mechanisms as ...

Binding mechanism of ATP and EGFR inhibitors revealed by ...

The overexpression or mutation of the kinase domain of the epidermal growth factor ... interaction of ATP and the binding site. We also find that a ...

Dual clathrin and integrin signaling systems regulate growth factor ...

EGF stimulation caused the appearance of pronounced EGFR clusters and a 2.4-fold increase in its correlation with clathrin (C = 0.36 ± 0.15) ...

A comprehensive pathway map of epidermal growth factor receptor ...

The epidermal growth factor receptor (EGFR) signaling pathway is one of the most important pathways that regulate growth, survival, proliferation, ...

Cell-Based Sensors for the Detection of EGF and EGF-Stimulated ...

Epidermal growth factor (EGF)-mediated activation of EGF receptors (EGFRs) has become an important target in drug development due to the ...