- About Mutations in the RET Gene🔍
- Definition of RET gene🔍
- RET gene mutations 🔍
- A comprehensive overview of the relationship between RET gene ...🔍
- RET inhibitors🔍
- RET mutation heterogeneity in primary advanced medullary thyroid ...🔍
- Prognostic Significance of Somatic RET Oncogene Mutations in ...🔍
- Precision oncology for RET|related tumors🔍
About Mutations in the RET Gene
About Mutations in the RET Gene
Having a mutation in this gene does not mean you will definitely develop cancer. It means that you have an increased risk of developing certain types of ...
RET gene: MedlinePlus Genetics
The RET gene provides instructions for producing a protein that is involved in signaling within cells. Learn about this gene and related health conditions.
5979 - Gene ResultRET ret proto-oncogene [ (human)] - NCBI
RET gene alterations (copy number gain and rearrangement) exist in all RET-positive samples. RET-positive expression is a relatively independent ...
Having a RET pathogenic variant, also known as a mutation, means a person has a version of the RET gene that does not work properly.
RET gene mutations associated with nonsyndromic pheochromocytoma change single amino acids in the RET protein. As in multiple endocrine ...
About Mutations in the RET Gene
What can I do about my cancer risk if I have a RET mutation? Your genetic counselor will review your results. They will talk with you about what ...
Definition of RET gene - NCI Dictionary of Cancer Terms
RET gene mutations have been found in certain genetic conditions, including MEN2 syndrome and Hirschsprung disease, and in some types of cancer, including non- ...
RET gene mutations (genotype and phenotype) of multiple ...
This review describes the discovery of the RET proto-oncogene, the association between genotype and phenotype, and the role of mutation analysis on diagnosis ...
A comprehensive overview of the relationship between RET gene ...
Rearranged during transfection (RET) mutation is related to cell proliferation, invasion, and migration. Many invasive tumors (e.g., non-small ...
RET inhibitors: A treatment for any RET-altered cancer
Some cancers are driven by a mutation in the RET gene or a rearrangement in gene's DNA. RET inhibitors target these genetic abnormalities to ...
Minireview: RET: Normal and Abnormal Functions - Oxford Academic
The RET gene encodes a single-pass transmembrane receptor tyrosine kinase. RET is the oncogene that causes papillary thyroid carcinoma and medullary thyroid ...
RET (multiple endocrine neoplasia type 2 gene) - UpToDate
The pathogenic variant in RET is de novo in 5 to 15 percent and 50 percent of patients with MEN2A and MEN2B, respectively [2]. Thus, a negative ...
Entry - *164761 - RET PROTOONCOGENE; RET - OMIM
Mutations in the RET gene are associated with multiple endocrine neoplasia, type IIA (MEN2A; 171400), multiple endocrine neoplasia, type IIB (MEN2B; 162300), ...
RET mutation heterogeneity in primary advanced medullary thyroid ...
This study demonstrated that in about 20% of cases a different RET mutation profile can be found when comparing primary tumor and its corresponding metastases.
Prognostic Significance of Somatic RET Oncogene Mutations in ...
Genetic analysis revealed a somatic RET mutation in 43 out of 100 (43%) sporadic MTCs (Fig. 1A). The majority of RET mutations (34 of 43, 79%) were located at ...
Overview ... The RET gene (ret proto-oncogene), encodes the proto-oncogene tyrosine-protein kinase receptor Ret, a receptor tyrosine kinase (RTK). Activating ...
Precision oncology for RET-related tumors - Frontiers
RET gene mutations and fusions are known to be gain-of-function driver events in many cancer types (Figure 1). FIGURE 1. www.frontiersin.org.
RET proto-oncogene - Wikipedia
The RET proto-oncogene encodes a receptor tyrosine kinase for members of the glial cell line-derived neurotrophic factor (GDNF) family of extracellular ...
An Update on The Prevalence of Germline RET Mutations - ARPI
Conclusions: a) RET genetic screening is informative in both hereditary and sporadic MTC; b) the prevalence of different mutations varies with ...
RET Proto-Oncogene Testing - Medical Clinical Policy Bulletins
Genetic testing for RET germline mutation has shown 100 % sensitivity and specificity for identifying those at risk for developing inherited medullary thyroid ...