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Activation and adoptive transfer of Epstein–Barr virus|specific ...


Activation and adoptive transfer of Epstein-Barr virus-specific ...

The treatment of Epstein-Barr virus (EBV)-associated lymphoproliferative disease (PTLD) in EBV seronegative solid organ transplant recipients who acquire ...

Activation and adoptive transfer of Epstein–Barr virus-specific ...

We have developed a protocol for activating autologous EBV-specific CTL lines from these patients and show their potential use for immunotherapy against PTLD ...

Activation and Adoptive Transfer of Epstein-Barr Virus-Specific ... - jstor

Activation and adoptive transfer of Epstein-Barr virus-specific cytotoxic T cells in solid organ transplant patients with posttransplant lymphoproliferative ...

Adoptive transfer of EBV-specific T cells results in sustained clinical ...

Patients with recurrent or refractory Epstein Barr virus (EBV)-positive nasopharyngeal carcinoma (NPC) continue to have poor outcomes.

Activation and adoptive transfer of Epstein-Barr virus-specific ...

We have developed a protocol for activating autologous EBV-specific CTL lines from these patients and show their potential use for immunotherapy against PTLD in ...

Adoptive Cell Transfer of Allogeneic Epstein–Barr Virus-Specific T ...

We describe for the first time a novel treatment approach for PTSMT by adoptive cell transfer (ACT) of EBV-specific T cells to a 20-year-old patient.

Activation and adoptive transfer of Epstein-Barr virus-specific ...

Activation and adoptive transfer of Epstein-Barr virus-specific cytotoxic T cells in solid organ transplant patients with post transplant lymphoproliferative ...

Adoptive Transfer of Epstein-Barr Virus (EBV) Nuclear Antigen 1 ...

In vivo expansion of transferred EBNA-1–specific T cells was observed in eight of 10 patients after a median of 16 days following adoptive ...

Rapid Generation of EBV-Specific Cytotoxic T Lymphocytes ...

Strategies to reconstitute immunity by adoptive transfer of EBV-specific cytotoxic T lymphocyte (CTL) therapy while highly effective in the HSCT setting where ...

Reconstitution of EBV-directed T cell immunity by adoptive transfer ...

As a result, reactivation of Epstein-Barr virus (EBV) is a frequent complication that may be treated by adoptive transfer of donor-derived EBV-specific T cells.

EBV-induced T-cell responses in EBV-specific and nonspecific ...

Despite the diverse repertoire of immunomodulatory mechanisms employed by EBV-positive cancers, adoptive transfer of EBV-specific T cells has demonstrated ...

Adoptive transfer of allogeneic Epstein–Barr virus (EBV)

A patient with relapsed NPC, refractory to conventional treatments, received salvage adoptive immunotherapy with EBV-specific CTLs reactivated ex vivo.

Activation and adoptive transfer of Epstein-Barr virus-specific ...

Title, Activation and adoptive transfer of Epstein-Barr virus-specific cytotoxic T cells in solid organ transplant patients with posttransplant ...

Epstein-Barr virus–specific T cell therapy for progressive multiple ...

CONCLUSION. EBV-specific adoptive T cell therapy was well tolerated. Clinical improvement following treatment was associated with the potency of ...

How I treat EBV lymphoproliferation | Blood - ASH Publications

Epstein-Barr virus (EBV) lymphoproliferative disease (LPD) is the result of the outgrowth of EBV-infected B cells that would normally be controlled by an ...

Adoptive cellular immunotherapy for Epstein-Barr virus-associated ...

After primary EBV infection, most viral antigens are expressed during the lytic stage while the virus is replicating. In EBV-infected B-cells, there is ...

The interplay between Epstein-Barr virus and the immune system

expansion of EBV-specific T cells. Indeed, the infusion of virus-specific cytotoxic T lymphocytes has proved not only to be safe and effective, but also capable ...

Long–term restoration of immunity against Epstein–Barr virus ...

Adoptive transfer of antigen–specific cytotoxic T lymphocytes (CTLs) offers safe and effective therapy for certain viral infections and ...

Targeted Activation of Human Vγ9Vδ2-T Cells Controls Epstein-Barr ...

Adoptive transfer of pamidronate-expanded Vγ9Vδ2-T cells alone effectively prevented EBV-LPD in Rag2−/−γc−/− mice and induced EBV-LPD regression ...

Adoptive Transfer of Polyclonal, EBV-Specific Cytotoxic T-Cell Lines ...

EBV-transformed B-cell lines (LCLs) are excellent antigen-presenting cells (APCs) that express nine virus-encoded proteins and can be used to stimulate and ...