Acute localized administration of tetrahydrobiopterin and chronic ...

Acute localized administration of tetrahydrobiopterin and chronic systemic atorvastatin treatment restore cutaneous microvascular function in ...

Acute localized administration of tetrahydrobiopterin and chronic systemic atorvastatin treatment restore cutaneous microvascular function ...

Acute localized administration of tetrahydrobiopterin and chronic ...

Acute localized administration of tetrahydrobiopterin and chronic systemic atorvastatin treatment restore cutaneous microvascular function ...

Local tetrahydrobiopterin administration augments reflex cutaneous ...

We hypothesized that acute local BH 4 administration or arginase inhibition would similarly augment reflex vasodilation in aged skin during passive whole body ...

Tetrahydrobiopterin: Beyond Its Traditional Role as a Cofactor - MDPI

However, severe PAH deficiency leads to PKU, characterized by the persistent accumulation of Phe greater than 360 mmol/L, which becomes toxic to the brain and ...

Intraplantar injection of tetrahydrobiopterin induces nociception in ...

Tetrahydrobiopterin (BH4) is implicated in the development and maintenance of chronic pain. ... acute nociceptive effects of intraplantar injection of BH4. BH4 ...

Tetrahydrobiopterin in Cardiovascular Health and Disease

For example, in chronic smokers, acute BH4 administration improves ... localized to the endothelial cell layer in normal mice (52). Contrastingly ...

Brain Kynurenine and BH4 Pathways: Relevance to the ... - Frontiers

Consistent with clinical findings, both acute or chronic immune challenges ... Chronic administration of tianeptine balances lipopolysaccharide-induced ...

Reduction of Neuropathic and Inflammatory Pain through Inhibition ...

Acute administration of SPRi3 reduced plasma BH4 levels without ... Tetrahydrobiopterin in striatum: localization in dopamine nerve ...

Acute oral tetrahydrobiopterin administration ameliorates ...

Acute oral tetrahydrobiopterin administration ameliorates endothelial dysfunction in systemic sclerosis. D.R. Machin1, H.L. Clifton2, R.S. Richardson3, ...

Relationship between Tetrahydrobiopterin and Portal Hypertension ...

BH4 concentration in liver tissue has little relation to the severity of portal hypertension in patients with chronic liver disease.

J Physiol - Content Listing - Medscape

... localization of a cardiac potassium channel. October ... Acute localized administration of tetrahydrobiopterin and chronic systemic atorvastatin treatment ...

Tetrahydrobiopterin administration facilitates amphetamine-induced ...

Results: This sub-chronic administration of BH4 rescued ... Moreover, we recently showed that increased BH4 brain levels induced by acute administration ...

Tetrahydrobiopterin Role in human umbilical vein endothelial ...

Holowatz, Acute localized administration of tetrahydrobiopterin and chronic systemic atorvastatin treatment restore cutaneous microvascular function in ...

The complete European guidelines on phenylketonuria: diagnosis ...

Long-term treatment with tetrahydrobiopterin increases phenylalanine tolerance in children with severe phenotype of phenylketonuria. Mol ...

Hypercholesterolemia and Human Skin Blood Flow - W. Kenney

Holowatz, Lacy A; Kenney, W Larry (2011) Acute localized administration of tetrahydrobiopterin and chronic systemic atorvastatin treatment restore cutaneous ...

371. Ixmyelocel T: A Cellular Therapy for the Treatment of Severe ...

Treatment of Severe, Chronic Cardiovascular ... by administration of BH4. Levels of restenosis ... surgical bypass is successful with localized coronary lesions, ...

Effectiveness of Laser Doppler Perfusion Monitoring in the ...

42. Holowatz, L.A. ∙ Kenney, W.L.. Acute localized administration of tetrahydrobiopterin and chronic systemic atorvastatin treatment restore cutaneous ...

Inhalation of the Nitric Oxide Synthase Cofactor Tetrahydrobiopterin ...

Constitutive NO synthase (cNOS) and inducible NOS (iNOS) have been localized ... treatment of patients with acute or chronic pulmonary diseases ( ...

Tetrahydrobiopterin Administration Augments Exercise-Induced ...

These results demonstrate the efficacy of acute BH 4 administration to improve both resistance and conduit vessel endothelial function in SSc.