Additional file 10 of An aging|related immune landscape in the ...

Additional file 10 of An aging-related immune landscape in the ...

posted on 2024-08-14, 04:44 authored by Jianjie Lv, Chun Zhang, Xiuxing Liu, Chenyang Gu, Yidan Liu, Yuehan Gao, Zhaohao Huang, Qi Jiang, Binyao Chen, ...

In addition, spleen is also the important organ and site that facilitates cellular and humoral immune responses [19]. DenisA et al. employed ...

The immune subtypes and landscape of sarcomas - PMC - NCBI

We clustered the 251 samples in the dataset from TCGA based on expression of 1914 immune-related genes (Additional file 3: Fig. S3A) and ...

Comprehensive Profiling of an Aging Immune System Reveals ...

In humans, proportions of the circulating GZMK+CD8+ T cell population that shares transcriptional and epigenetic signatures with mouse Taa cells ...

Single-cell profiling of immune system alterations in lymphoid ...

To create a comprehensive immune-phenotyping map as a resource to compare cellular changes between young and aged mice, we aimed to measure age- ...

Furthermore, regulatory CD8 T cells marked by Klra decreased with aging, while a subpopulation of exhausted-like CD8 T cells expanded, retaining potent ...

Identification of stage-related and severity-related biomarkers and ...

2D, I and Additional file 10: Table S4) between DF (n = 15) and DHF ... Immune landscape related to characteristics of dengue patients.

A human circulating immune cell landscape in aging and COVID-19

In addition, senescence of the immune system in the elderly has been termed “inflammaging”, which refers to increased levels of tissue and ...

Single-cell RNA sequencing reveals evolution of immune landscape ...

Using single-cell transcriptomics and flow cytometry, we unveiled large-scale comprehensive longitudinal changes in immune cell composition ...

Integration of bulk RNA sequencing and single-cell analysis reveals ...

... related to these DDR regulators (Additional file: Figure S1F). To ... DDR C2 was primarily driven by immune response-related functions ...

Effects of sex and aging on the immune cell landscape as assessed ...

Moreover, cell–cell communication analysis revealed evidence of increased activity of the BAFF/APRIL systems in females. Notably, aging ...

iGATE analysis improves the interpretability of single-cell immune ...

... additional 19% of data variation, broadly correlates with age. ... immune landscape (10). Most importantly, the techniques developed in ...

Spatiotemporal Immune Landscape of Colorectal Cancer Liver ...

Other M2 polarization–related genes such as MARCO (35) were also ... Marker genes for all immune cell subsets. - xlsx file. Supplementary Table S3.

(PDF) An aging-related immune landscape in the hematopoietic ...

Conclusions Overall, aging extensively alters the cellular composition and function of the HIS. These findings could potentially give high- ...

Aging promotes reorganization of the CD4 T cell landscape toward ...

Age-associated changes in CD4 T-cell functionality have been linked to chronic inflammation and decreased immunity.

Identification of mRNA vaccines and conserved ferroptosis related ...

The two clusters showed the different trend of immune cell infiltration. Further, the immune cell composition was significantly different among ...

The chromatin accessibility signature of human immune aging stems ...

This signature is borne by memory CD8+ T cells, which exhibited an aging-related loss in binding of NF-κB and STAT factors. Thus, our study ...

Longitudinal Multi-omic Immune Profiling Reveals Age-Related ...

We find that T cells specifically accumulate age-related transcriptional changes more than other immune cells, independent from inflammation and ...

Multi-modal Single-Cell Analysis Reveals Brain Immune Landscape ...

Aging and gut microbiota dysbiosis that reshape brain immune cell plasticity and homeostasis has not been fully delineated. Using Cellular ...

Transcriptional and Immune Landscape of Cardiac Sarcoidosis

Using multichannel immunofluorescence staining, we validated immune cell populations identified by single-nucleus RNA sequencing, determined ...