Adenosine A2A Receptor|Containing Heteromers and ...

Adenosine A2A Receptors and A2A Receptor Heteromers as Key ...

Abstract. A very significant density of adenosine A2A receptors (A2ARs) is present in the striatum, where they are preferentially localized postsynaptically in ...

Adenosine A2A Receptor-Containing Heteromers and ...

This chapter aims at presenting the partners of the A 2A R with a special focus on the potential of their ligands, agonists, antagonists and allosteric ...

Receptor heteromerization in adenosine A2A receptor signaling

The A2A/D2 heteromeric receptor complex. Evidence has accumulated that intramembrane antagonistic receptor–receptor interactions between ...

Adenosine A2A-dopamine D2 receptor–receptor heteromers ...

These include adenosine A2A receptor–dopamine D2 receptor heteromers, which are most probably localized in the dendritic spines of the striatopallidal GABAergic ...

Adenosine A2A receptor - Wikipedia

The adenosine A2A receptor, also known as ADORA2A, is an adenosine receptor, and also denotes the human gene encoding it.

Adenosine A2A Receptor - an overview | ScienceDirect Topics

Adenosine A2A receptors are selectively located on striatopallidal neurons and are capable of forming functional heteromeric complexes with dopamine D2 and ...

Decreased striatal adenosine A2A-dopamine D2 receptor ... - Nature

According to the adenosine hypothesis of schizophrenia, the classically associated hyperdopaminergic state may be secondary to a loss of ...

Adenosine A2A Receptor-Antagonist/Dopamine D2 Receptor ...

Adenosine A2A Receptor-Antagonist/Dopamine D2 Receptor-Agonist Bivalent Ligands as Pharmacological Tools to Detect A2A-D2 Receptor Heteromers.

Adenosine A1-A2A receptor heteromers: new targets for caffeine in ...

The analysis of the function of A1-A2A receptor heteromers during chronic treatment with caffeine gives new clues about the well-known ...

Allosteric interactions between agonists and antagonists within the ...

The adenosine A2A receptor (A2AR)-dopamine D2 receptor (D2R) heteromer is a target for the nonselective adenosine receptor antagonist caffeine.

Adenosine A1-A2A Receptor Heteromer as a Possible ... - Frontiers

This article is part of the Research Topic Adenosine Receptors and Neurodegeneration View all 8 articles Adenosine A 1 -A 2A Receptor Heteromer as a Possible ...

Expression of the Adenosine A2A-A3 Receptor Heteromer in ... - MDPI

The aim of this paper was to look for the expression and function of the A 2A /A 3 receptor heteromer (A 2A A 3 Het) in neurons and microglia.

Adenosine A1-A2A receptor heteromers - IMR Press

Among the four cloned adenosine receptors (A1,. A2A, A2B and A3 receptors), A1 and A2A receptors are the ones predominantly expressed in the brain. Caffeine is ...

Behavioral control by striatal adenosine A2A‐dopamine D2 receptor ...

The relative expression of GPCR heteromers remains a matter of intense debate. Recent studies support that adenosine A2A receptors (A2AR) and ...

Adenosine A2A Receptors and A2A Receptor Heteromers as Key ...

Three different types of A2ARs can be pharmacologically dissected by their ability to bind ligands with different affinity and can therefore provide ...

Dopamine D2 and Adenosine A2A Receptors Regulate NMDA ...

Among these, dopamine D2 and adenosine A2A receptors are highly enriched in striatal neurons and exhibit strong interactions whose physiological ...

Adenosine A2A Receptor and Dopamine D3 Receptor Interactions

Adenosine A2A and dopamine D2 receptors have been shown previously to form heteromeric complexes and interact at the level of agonist binding, G protein ...

Allosteric interactions between agonists and antagonists within the ...

The adenosine A2A receptor (A2AR)-dopamine D2 receptor (D2R) heteromer is a target for the nonselective adenosine receptor antagonist caffeine. This study ...

Receptor heteromerization in adenosine A2A receptor signaling

Recently evidence has been presented that adenosine A2A and dopamine D₂ receptors form functional heteromeric receptor complexes as demonstrated in human ...

Allosteric Interactions between Adenosine A 2A and Dopamine D 2 ...

Adenosine and dopamine interact antagonistically in living mammals. These interactions are mediated via adenosine A2A and dopamine D2 receptors (R).