• Adenosine A2A receptor🔍
• Adenosine A2A Receptor🔍
• Human Adenosine A2A Receptor🔍
• Adenosine A2A Receptors in Psychopharmacology🔍
• The caffeine|binding adenosine A2A receptor induces age|like HPA ...🔍
• Adenosine|A2A Receptor Pathway in Cancer Immunotherapy🔍
• Adenosine A2A Antagonists🔍
• Adenosine A2A Receptor as a Drug Discovery Target🔍

Adenosine A2A receptor - Wikipedia

Adenosine A2A receptor ... The adenosine A2A receptor, also known as ADORA2A, is an adenosine receptor, and also denotes the human gene encoding it.

Adenosine A2A Receptor - an overview | ScienceDirect Topics

Adenosine A2A Receptor ... Adenosine A2A Receptor is a subtype of adenosine receptors that is Gs-protein-coupled and can increase intracellular cAMP levels, ...

135 - Gene ResultADORA2A adenosine A2a receptor [ (human)]

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided ...

Human Adenosine A2A Receptor: Molecular Mechanism ... - Frontiers

In this review we analyze the structural data reported for A 2A R that described for the first time the binding of mode of antagonists.

Adenosine A2A Receptors in Psychopharmacology: Modulators of ...

The adenosine A2A receptor (A2AR) is in the center of a neuromodulatory network affecting a wide range of neuropsychiatric functions by interacting with and ...

The caffeine-binding adenosine A2A receptor induces age-like HPA ...

Caffeine is associated with procognitive effects in humans by counteracting overactivation of the adenosine A2A receptor (A2AR), ...

Adenosine-A2A Receptor Pathway in Cancer Immunotherapy

This review will discuss the role of the adenosine-A2AR pathway in the tumor microenvironment and summarize recent advances of A2AR-cancer related studies.

Adenosine A2A Antagonists | Parkinson's Foundation

Adenosine A2A antagonists are used in Parkinson's disease treatment to reduce "off" times.

Adenosine A2A Receptor as a Drug Discovery Target

Following the discovery of adenosine, almost a century of intense research on adenosine receptors has led to the selection of the adenosine A2A receptor as a ...

p29274 · aa2ar_human - UniProt

Adenosine receptor A2a. Gene. ADORA2A. Status. UniProtKB reviewed (Swiss-Prot). Organism. Homo sapiens (Human). Amino acids. 412 (go to sequence). Protein ...

Adenosine A2A receptor antagonists: from caffeine to selective non ...

Adenosine is a short-lived autocrine/paracrine mediator that acts pharmacologically at four different adenosine receptors in a manner opposite ...

Definition of adenosine A2A receptor antagonist NIR178 - NCI Drug ...

Upon administration, A2AR antagonist NIR178 selectively binds to and inhibits A2AR expressed on T lymphocytes. This prevents tumor-released adenosine from ...

A 2A receptor - IUPHAR/BPS Guide to PHARMACOLOGY

Human A2A adenosine receptor bound to an antagonist. PDB Id ... Crystal structure of stabilized A2A adenosine receptor A2AR-StaR2-bRIL in complex with PSB36.

Endothelial adenosine A2a receptor-mediated glycolysis is essential ...

Adenosine/adenosine receptor-mediated signaling has been implicated in the development of various ischemic diseases, including ischemic ...

Retrograde adenosine/A2A receptor signaling facilitates excitatory ...

We identified adenosine/A 2A receptor (A 2A R) as a retrograde signaling pathway underlying presynaptic long-term potentiation (LTP) at a hippocampal ...

Dual roles of the adenosine A2a receptor in autoimmune ...

A2aR activation exerts a complex pattern in chronic autoimmune neurodegeneration: while providing anti-inflammatory effects on T cells and thus ...

How do adenosine A2A receptors regulate motor function?

This review addresses how adenosine A 2A receptors are involved with the control of motor function via the basal ganglia-thalamocortical circuit.

Adenosine A2a Receptor Agonists Products - R&D Systems

The activity of ADORA2A, a G protein-coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase.

Crystal structure of the adenosine A2A receptor bound to an ... - PNAS

Here we report the crystal structure of A 2A receptor bound to compound 1 (Cmpd-1), a novel A 2A R/N-methyl d-aspartate receptor subtype 2B (NR2B) dual ...

AAR-002 - Anti-Adenosine A2A Receptor Antibody - Alomone Labs

Anti-Adenosine A2A Receptor Antibody from Alomone Labs is a highly specific rabbit polyclonal Ab directed against mouse ADORA2a. Applications: ICC, IHC, WB.