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Adenosine as a modulator of brain activity
Adenosine as a modulator of brain activity - PubMed
The endogenous neuromodulator adenosine controls and integrates a wide range of brain functions. Consequently, dysfunction of the adenosine system is ...
Role of Adenosine as a Modulator of Synaptic Activity in the Central ...
Adenosine receptors are located throughout the nervous system and extracellular adenosine can effectively modulate neuronal activity. This chapter summarizes ...
Adenosine-Based Modulation of Brain Activity - PMC
The purine ribonucleoside adenosine is an endogenous modulator of brain function uniquely positioned to integrate a wide variety of signalling pathways.
Adenosine as a neuromodulator in neurological diseases
Adenosine is a modulator of brain function uniquely positioned to integrate excitatory and inhibitory neurotransmission. The past few years brought a wealth ...
The Role and Regulation of Adenosine in the Central Nervous System
Abstract Adenosine is a modulator that has a pervasive and generally inhibitory effect on neuronal activity. Tonic activation of adenosine ...
Adenosine Differentially Modulates Synaptic Transmission of ...
In the central nervous system, adenosine is generally an inhibitory neuromodulator; adenosine binding to A1 receptors decreases the intrinsic excitability of ...
How does adenosine control neuronal dysfunction and ...
2005) in an activity-dependent manner (Fields 2006); (iv) ATP is a paracrine modulator of astrocytes and a neuron- or microglia-to-astrocyte ...
Adenosine signalling to astrocytes coordinates brain metabolism ...
Here we show, using experimental in vitro and in vivo animal models, that neuronal activity-dependent metabolic activation of astrocytes is ...
Adenosine as a modulator of brain activity - Research With Rutgers
The endogenous neuromodulator adenosine controls and integrates a wide range of brain functions. Consequently, dysfunction of the adenosine system is ...
Adenosine as a modulator of brain activity. - Abstract - Europe PMC
The endogenous neuromodulator adenosine controls and integrates a wide range of brain functions. Consequently, dysfunction of the adenosine system is ...
Adenosine as a neuromodulator - Johns Hopkins University
Evidence from many sources implicates adenosine in brain function. Whether adenosine is a neurotransmitter or neuromodulator is unclear. Indeed, the ...
THE ROLE AND REGULATION OF ADENOSINE - Annual Reviews
Tonic activation of adenosine receptors by adenosine that is normally present in the extracellular space in brain tissue leads to inhibitory effects that appear ...
Metabolic Aspects of Adenosine Functions in the Brain - Frontiers
The knockout mice show undetectable ADA activity, increased adenosine in total brain extracts, slightly reduced brain size, alterations in explorative behavior, ...
Adenosine as a Modulator of Brain Activity | Request PDF
... Adenosine is an ubiquitous, predominantly inhibitory neuromodulator in the central nervous system (CNS) [1] involved in numerous physiological (e.g., ...
Emerging roles of dysregulated adenosine homeostasis in brain ...
Adenosine is a purine nucleoside and neuromodulator in the brain. It is also an essential component of energy production pathways, cellular ...
Adenosine Inhibits Evoked Synaptic Transmission Primarily by ...
Adenosine is a potent modulator of neuronal activity throughout the nervous system. Previous evidence sug- gests that adenosine presynaptically inhibits ...
Neuronal adenosine release, and not astrocytic ATP release ... - PNAS
Multiple Enzymes Degrade Extracellular ATP in Brain Tissue, Whereas only Nt5e Degrades AMP to Adenosine. · Endogenous A1 Receptor Activation During Cortical ...
The Role and Regulation of Adenosine in the Central Nervous System
Adenosine is a modulator that has a pervasive and generally inhibitory effect on neuronal activity. Tonic activation of adenosine receptors by adenosine ...
Adenosine receptor signaling: a key to opening the blood–brain door
The aim of this review is to outline evidence that adenosine receptor (AR) activation can modulate blood–brain barrier (BBB) permeability ...
Role of Adenosine as a Modulator of Synaptic Activity in the Central ...
Abbracchio, G protein-dependent activation of phospholipase C by adenosine A, receptors in rat brain, Mol. · Arch, The control of the metabolism and the hormonal ...